Source: BEFREE

Variant Gene DSI v DPI v Chr Position Consequence Alleles Class AF EXOME AF GENOME Disease Score vda EI vda N. PMIDs First Ref. Last Ref.
dbSNP: rs4986893
rs4986893
CYP2C19
0.827 0.240 10 94780653 stop gained G/A snv 5.4E-03 1.5E-03
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2007 2007
dbSNP: rs753254929
rs753254929
APEX1 ; OSGEP
0.851 0.080 14 20455915 missense variant G/A;C snv 1.6E-05
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2007 2007
dbSNP: rs760943842
rs760943842
ZNF436
0.851 0.080 1 23362976 missense variant G/A snv 4.0E-05 1.4E-05
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2007 2007
dbSNP: rs777175289
rs777175289
CYP3A5 ; ZSCAN25
1.000 0.080 7 99664085 synonymous variant T/C snv 4.5E-06
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2007 2007
dbSNP: rs868063722
rs868063722
CYP2C19
1.000 0.080 10 94775077 missense variant C/T snv
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2007 2007
dbSNP: rs10012
rs10012
CYP1B1 ; CYP1B1-AS1
0.716 0.280 2 38075247 missense variant G/C snv 0.31 0.36
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs141726378
rs141726378
COMT ; MIR4761
1.000 0.080 22 19963693 missense variant C/G;T snv 4.0E-06; 1.2E-05
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs1622002
rs1622002
GSTT2B
1.000 0.080 22 23958393 missense variant C/T snv 5.3E-02 6.6E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs2293347
rs2293347
EGFR
0.851 0.080 7 55201223 synonymous variant C/T snv 0.14 9.5E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs373572
rs373572
RAD18
0.882 0.120 3 8913705 missense variant C/T snv 0.68 0.70
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs60718122
rs60718122
GSTT2
1.000 0.080 22 23982936 missense variant G/A snv 1.5E-03
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs751648572
rs751648572
SOD2
1.000 0.080 6 159682631 missense variant A/C snv 4.1E-06
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs754845817
rs754845817
ALDH2
1.000 0.080 12 111790494 missense variant G/A snv 1.6E-05 1.4E-05
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs759684602
rs759684602
MPO
1.000 0.080 17 58279136 missense variant T/C snv 2.0E-05 7.0E-06
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs781598341
rs781598341
SOD2
0.827 0.240 6 159682510 missense variant T/C snv 4.0E-06
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2008 2008
dbSNP: rs17576
rs17576
MMP9
0.557 0.760 20 46011586 missense variant A/G snv 0.39 0.36
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs17577
rs17577
MMP9 ; SLC12A5-AS1
0.649 0.520 20 46014472 missense variant G/A;C snv 0.16
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs1805377
rs1805377
XRCC4
0.689 0.480 5 83353124 splice acceptor variant G/A snv 0.23 0.25
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs2032582
rs2032582
ABCB1
0.538 0.800 7 87531302 missense variant A/C;T snv 0.54; 3.8E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs369410616
rs369410616
MUTYH
0.752 0.280 1 45329400 missense variant C/T snv 2.0E-05 2.8E-05
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs4645981
rs4645981
CASP9 ; DNAJC16
0.790 0.160 1 15524988 intron variant G/A;C snv
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2009 2009
dbSNP: rs1001581
rs1001581
XRCC1
1.000 0.080 19 43561236 intron variant C/T snv 0.38
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2010 2010
dbSNP: rs1042489
rs1042489
BIRC5
0.851 0.160 17 78224125 3 prime UTR variant T/C snv 0.40
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2010 2010
dbSNP: rs1138272
rs1138272
GSTP1
0.611 0.600 11 67586108 missense variant C/T snv 5.9E-02 5.5E-02
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2010 2010
dbSNP: rs1228223399
rs1228223399
CYP1B1 ; CYP1B1-AS1
1.000 0.080 2 38075045 missense variant G/A snv 5.0E-06
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		0.010 1.000 1 2010 2010