rs1052133
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Myeloid Leukemia, Chronic
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0.010 |
GeneticVariation
|
BEFREE |
OGG1 rs1052133 Polymorphism and Genetic Susceptibility to Chronic Myelogenous Leukaemia
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30912416 |
2019 |
rs1052133
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Hepatitis C, Chronic
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0.010 |
GeneticVariation
|
BEFREE |
Urinary 8-hydroxydeoxyguanosine in relation to XRCC1 rs25487 G/A (Arg399Gln) and OGG1 rs1052133 C/G (Ser326Cys) DNA repair genes polymorphisms in patients with chronic hepatitis C and related hepatocellular carcinoma.
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31354343 |
2019 |
rs1052133
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Cervical Squamous Cell Carcinoma
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0.010 |
GeneticVariation
|
BEFREE |
Our findings support associations of the hOGG1 Ser326Cys polymorphism with CSCC carcinogenesis and susceptibility to HR-HPV infection.
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30648893 |
2019 |
rs1052133
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Cervical Intraepithelial Neoplasia
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0.010 |
GeneticVariation
|
BEFREE |
hOGG1 Ser326Cys was genotyped through modified allele mismatch amplification polymerase chain reaction in 1200 healthy controls, 400 cervical intraepithelial neoplasia (CIN) grade III cases, and 400 CSCC cases.
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30648893 |
2019 |
rs1052133
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Human papilloma virus infection
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0.010 |
GeneticVariation
|
BEFREE |
Association of Base Excision Repair Gene hOGG1 Ser326Cys Polymorphism with Susceptibility to Cervical Squamous Cell Carcinoma and High-Risk Human Papilloma Virus Infection in a Chinese Population.
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30648893 |
2019 |
rs1052133
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Hepatitis C
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0.010 |
GeneticVariation
|
BEFREE |
For OGG1 (Ser326Cys), GG (Cys/Cys) genotype and G-allele were increased significantly in chronic HCV and HCC patients compared to the controls (<i>P</i><0.05).
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31354343 |
2019 |
rs1052133
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Papilloma
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0.010 |
GeneticVariation
|
BEFREE |
The hOGG1 Ser326Cys polymorphism may serve as a potential genetic biomarker of susceptibility to cervical cancer and HR-HPV infection.
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30648893 |
2019 |
rs1052133
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Carcinoma in situ of uterine cervix
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0.010 |
GeneticVariation
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BEFREE |
We further observed enrichment of the hOGG1 Ser326Cys polymorphism in the CIN III (p = 0.021) and CSCC (p < 0.001) stratified by age at first intercourse, with more significant enrichment (p = 0.036) in the HR-HPV infection group.
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30648893 |
2019 |
rs1052133
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Cardiovascular Diseases
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0.010 |
GeneticVariation
|
BEFREE |
Our aim was to evaluate the association of the OGG1-rs1052133 with total, cancer, and cardiovascular disease (CVD) mortality and to analyze its modulation by the Mediterranean diet, focusing especially on total vegetable intake as one of the main characteristics of this diet.
|
29305130 |
2018 |
rs1052133
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Malignant mesothelioma
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0.010 |
GeneticVariation
|
BEFREE |
Although there was no independent association between either <i>CAT</i> rs1001179 or <i>hOGG1</i> rs1052133 polymorphism and malignant mesothelioma, interaction between both polymorphisms showed a protective effect, OR<sub>int</sub> 0.27 (95% CI 0.10-0.77).
|
29520212 |
2018 |
rs1052133
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Nephroblastoma
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0.010 |
GeneticVariation
|
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
|
29937070 |
2018 |
rs1052133
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Childhood Kidney Wilms Tumor
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0.010 |
GeneticVariation
|
BEFREE |
Significant associations with Wilms tumor susceptibility were shown for hOGG1 rs1052133 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.96, P = .030), FEN1 rs174538 (dominant: adjusted OR = 0.66, 95% CI = 0.45-0.95, P = .027; recessive: adjusted OR = 0.54, 95% CI = 0.32-0.93 P = .027), and FEN1 rs4246215 (dominant: adjusted OR = 0.55, 95% CI = 0.38-0.80, P = .002) polymorphisms.
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29937070 |
2018 |
rs1052133
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Neuroblastoma
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0.010 |
GeneticVariation
|
BEFREE |
Stratified analysis revealed that rs1052133</span> GC/CC carriers were less likely to develop neuroblastoma in subgroups of age >18 months, males, tumor that develops from retroperitoneal, mediastinum and clinical stage I+II+4s.
|
30519358 |
2018 |
rs1052133
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Subfertility, Male
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0.010 |
GeneticVariation
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BEFREE |
The hOGG1 Ser326Cys polymorphism and male subfertility in Taiwanese patients with varicocele.
|
29582449 |
2018 |
rs1052133
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Leukemia, Myelocytic, Acute
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0.010 |
GeneticVariation
|
BEFREE |
The OGG1 S326C CC genotype (associated with lower OGG1 activity) was observed more frequently in patients with AML relapse [28.9 vs. 8.9%, odds ratio (OR) = 4.10, 95% confidence interval (CI) = 1.35-12.70, P = 0.01].
|
29737460 |
2018 |
rs1052133
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Laryngeal Squamous Cell Carcinoma
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0.010 |
GeneticVariation
|
BEFREE |
Our meta-analysis results indicated that <i>hOGG1</i> Ser326Cys polymorphism may be associated with increased risk of HNSCC, especially in Caucasians, alcohol drinkers and the patients with laryngeal squamous cell carcinoma.
|
29560133 |
2018 |
rs1052133
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Varicocele
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0.010 |
GeneticVariation
|
BEFREE |
The hOGG1 Ser326Cys polymorphism and male subfertility in Taiwanese patients with varicocele.
|
29582449 |
2018 |
rs1052133
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Childhood Neuroblastoma
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0.010 |
GeneticVariation
|
BEFREE |
Stratified analysis revealed that rs1052133</span> GC/CC carriers were less likely to develop neuroblastoma in subgroups of age >18 months, males, tumor that develops from retroperitoneal, mediastinum and clinical stage I+II+4s.
|
30519358 |
2018 |
rs1052133
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Obesity
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0.010 |
GeneticVariation
|
BEFREE |
This study investigated the associations of OGG1 Ser326Cys SNP in relation to HIV and obes</span>ity on the susceptibility of low-birthweight (LBW) and pre-term birth (PTB) in SA women exposed to ambient air-pollution living in Durban.
|
29709520 |
2018 |
rs1052133
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Central neuroblastoma
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0.010 |
GeneticVariation
|
BEFREE |
Stratified analysis revealed that rs1052133</span> GC/CC carriers were less likely to develop neuroblastoma in subgroups of age >18 months, males, tumor that develops from retroperitoneal, mediastinum and clinical stage I+II+4s.
|
30519358 |
2018 |
rs1052133
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Nasopharyngeal carcinoma
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0.010 |
GeneticVariation
|
BEFREE |
No significant association was observed between hOGG1 Ser326Cys and ITGA2 C807T polymorphisms with NPC risk after adjustment for age, gender, ethnicity, cigarette smoking, alcohol and salted fish consumption.
|
29121049 |
2017 |
rs1052133
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Rectal Carcinoma
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0.010 |
GeneticVariation
|
BEFREE |
Subgroup analyses revealed significant association of OGG1 rs1052133 with rectal cancer risk.
|
28749454 |
2017 |
rs1052133
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Intraocular pressure disorder
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0.010 |
GeneticVariation
|
BEFREE |
Furthermore, there were thicker corneas, higher intraocular pressure (IOP) and a shorter axial length in patients carrying the mutant genotypes of <i>hOGG1</i> Ser326Cys (Ser/Cys + Cys/Cys), <i>APE1</i> Asp148Glu (Asp/Glu + Glu/Glu) and XRCC<i>1</i> Arg399Gln (Arg/Gln + Glu/Glu) than those carrying the corresponding wild-type genotypes.
|
28396513 |
2017 |
rs1052133
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Squamous cell carcinoma of oropharynx
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0.010 |
GeneticVariation
|
BEFREE |
We examined the influence of OGG1 c.977C>G (rs1052133), APEX1 c.444T>G (rs1130409), XRCC1 c.-77T>C (rs3213245), c.580C>T (rs1799782), c.839G>A (rs25489) and c.1196G>A (rs25487) single-nucleotide polymorphisms (SNPs), involved in base-excision repair (BER) pathway, on oropharyngeal squamous cell carcinoma (OPSCC) risk and prognosis.
|
27372710 |
2016 |
rs1052133
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Cancer of Digestive System
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|
0.010 |
GeneticVariation
|
BEFREE |
In our analysis, the hOGG1 Ser326Cys polymorphism was significantly associated with the risk of digestive system cancers (Cys/Cys vs. Ser/Ser: OR = 1.17, 95% CI = 1.00-1.35, P < 0.001; Cys/Cys vs. Cys/Ser + Ser/Ser: OR = 1.14, 95% CI = 1.00-1.29, P < 0.001).
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25323581 |
2015 |