Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.900 GeneticVariation BEFREE Among those without distant disease at diagnosis, CRC-specific survival differed by genotype only for NSAID users: each minor allele of rs4939827 was associated with worse survival [hazard ratio (HR) = 2.67, 95% confidence interval (CI): 1.33-5.37] and each minor allele of rs4464148 was associated with better survival (HR = 0.41, CI 0.18-0.94). 21910156

2011
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.900 GeneticVariation BEFREE Two recent genome-wide association studies (GWAS) identified three common variants in SMAD7 (rs4464148, rs4939827 and rs12953717) that confer modest susceptibility to colorectal cancer. 19357349

2009
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		T 0.900 GeneticVariation GWASDB Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. 18372901

2008
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.900 GeneticVariation GWASDB Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. 19011631

2008
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		T 0.900 GeneticVariation GWASCAT Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. 18372901

2008
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		T 0.900 GeneticVariation GWASCAT Across the four sample sets, the association between rs4939827 and CRC was highly statistically significant (P(trend) = 1.0 x 10(-12)). 17934461

2007
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		T 0.900 GeneticVariation GWASDB Across the four sample sets, the association between rs4939827 and CRC was highly statistically significant (P(trend) = 1.0 x 10(-12)). 17934461

2007
dbSNP: rs4939827
rs4939827
SMAD7
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.900 GeneticVariation BEFREE Across the four sample sets, the association between rs4939827 and CRC was highly statistically significant (P(trend) = 1.0 x 10(-12)). 17934461

2007