|
rs11209026
|
|
Psoriasis
|
|
0.900 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs20541
|
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
rs20541
|
|
Psoriasis
|
G |
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
rs610604
|
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
rs610604
|
|
Psoriasis
|
|
0.860 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs610604
|
|
Psoriasis
|
G |
0.860 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
rs33980500
|
|
Psoriasis
|
|
0.850 |
GeneticVariation
|
GWASDB |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
|
rs33980500
|
|
Psoriasis
|
T |
0.850 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
|
20953188 |
2010 |
|
rs11652075
|
|
Psoriasis
|
|
0.840 |
GeneticVariation
|
GWASDB |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
|
rs12191877
|
|
Psoriasis
|
|
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
|
20953188 |
2010 |
|
rs12191877
|
|
Psoriasis
|
T |
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
rs2201841
|
|
Psoriasis
|
|
0.830 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
rs2201841
|
|
Psoriasis
|
G |
0.830 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
rs17728338
|
|
Psoriasis
|
|
0.820 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |
|
rs17728338
|
|
Psoriasis
|
A |
0.820 |
GeneticVariation
|
GWASDB |
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
|
19169254 |
2009 |
|
rs2395029
|
|
Psoriasis
|
C |
0.820 |
GeneticVariation
|
GWASDB |
However, rs2395029 encoding the G2V polymorphism within the class I gene HCP5 (combined P = 2.13x10(-26) in U.S. cases) yielded the highest ORs with both PS and PSA (4.1 and 3.2 respectively).
|
18369459 |
2008 |
|
rs4112788
|
|
Psoriasis
|
|
0.820 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs4112788
|
|
Psoriasis
|
|
0.820 |
GeneticVariation
|
GWASDB |
Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.
|
19169255 |
2009 |
|
rs4795067
|
|
Psoriasis
|
G |
0.820 |
GeneticVariation
|
GWASDB |
All three loci were also associated with psoriatic arthritis (rs4795067, combined P = 1 × 10⁻⁵; rs10782001, combined P = 4 × 10⁻⁸; and rs12586317, combined P = 6 × 1⁻⁵) and purely cutaneous psoriasis (rs4795067, combined P = 1 × 10⁻⁸; rs10782001, combined P = 2 × 10⁻⁶; and rs12586317, combined P = 1 × 10⁻⁶).
|
20953189 |
2010 |
|
rs10484554
|
|
Psoriasis
|
|
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs10484554
|
|
Psoriasis
|
T |
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
|
18369459 |
2008 |
|
rs1250544
|
|
Psoriasis
|
G |
0.810 |
GeneticVariation
|
GWASDB |
Three of the shared loci are also genome-wide significantly associated with PS alone (10q22 at ZMIZ1, p(rs1250544) = 3.53 × 10(-8), 11q13 near PRDX5, p(rs694739) = 3.71 × 10(-09), 22q11 at YDJC, p(rs181359) = 8.02 × 10(-10)).
|
22482804 |
2012 |
|
rs12720356
|
|
Psoriasis
|
A |
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs2066808
|
|
Psoriasis
|
|
0.810 |
GeneticVariation
|
GWASDB |
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
|
20953190 |
2010 |
|
rs2066808
|
|
Psoriasis
|
|
0.810 |
GeneticVariation
|
GWASDB |
Association analyses identify six new psoriasis susceptibility loci in the Chinese population.
|
20953187 |
2010 |