|
rs1051730
|
|
Carcinoma of lung
|
T |
0.800 |
GeneticVariation
|
GWASCAT |
Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.
|
30104567 |
2018 |
|
rs1051730
|
|
Carcinoma of lung
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
Lung cancer susceptibility locus at 5p15.33.
|
18978790 |
2008 |
|
rs13181
|
|
Carcinoma of lung
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer.
|
23108145 |
2013 |
|
rs2736100
|
|
Carcinoma of lung
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
23143601 |
2012 |
|
rs2736100
|
|
Carcinoma of lung
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
|
21725308 |
2011 |
|
rs401681
|
|
Carcinoma of lung
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
|
18978787 |
2008 |
|
rs8034191
|
|
Carcinoma of lung
|
|
0.800 |
GeneticVariation
|
GWASCAT |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
rs8034191
|
|
Carcinoma of lung
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
|
18385738 |
2008 |
|
rs8034191
|
|
Carcinoma of lung
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.
|
18385676 |
2008 |
|
rs8034191
|
|
Carcinoma of lung
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
The risk of lung cancer was more than fivefold higher among those subjects who had both a family history of lung cancer and two copies of high-risk alleles rs8034191 (odds ratio [OR] = 7.20, 95% confidence interval [CI] = 2.21 to 23.37) or rs1051730 (OR = 5.67, CI = 2.21 to 14.60, both of which were located in the 15q24-25.1 locus, than among control subjects.
|
18780872 |
2008 |
|
rs3117582
|
|
Carcinoma of lung
|
|
0.760 |
GeneticVariation
|
GWASCAT |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
rs3117582
|
|
Carcinoma of lung
|
C |
0.760 |
GeneticVariation
|
GWASCAT |
Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
|
18978787 |
2008 |
|
rs11571833
|
|
Carcinoma of lung
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.
|
28604730 |
2017 |
|
rs11571833
|
|
Carcinoma of lung
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
|
27197191 |
2016 |
|
rs11571833
|
|
Carcinoma of lung
|
T |
0.750 |
GeneticVariation
|
GWASCAT |
We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).
|
24880342 |
2014 |
|
rs4488809
|
|
Carcinoma of lung
|
|
0.750 |
GeneticVariation
|
GWASCAT |
Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region.
|
31009812 |
2019 |
|
rs4488809
|
|
Carcinoma of lung
|
C |
0.750 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
23143601 |
2012 |
|
rs4488809
|
|
Carcinoma of lung
|
C |
0.750 |
GeneticVariation
|
GWASCAT |
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
|
21725308 |
2011 |
|
rs2853677
|
|
Carcinoma of lung
|
C |
0.740 |
GeneticVariation
|
GWASCAT |
The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).
|
27393504 |
2016 |
|
rs17879961
|
|
Carcinoma of lung
|
A |
0.730 |
GeneticVariation
|
GWASCAT |
We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).
|
24880342 |
2014 |
|
rs4975616
|
|
Carcinoma of lung
|
|
0.720 |
GeneticVariation
|
GWASCAT |
A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.
|
19654303 |
2009 |
|
rs7086803
|
|
Carcinoma of lung
|
A |
0.720 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
23143601 |
2012 |
|
rs753955
|
|
Carcinoma of lung
|
G |
0.720 |
GeneticVariation
|
GWASCAT |
The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).
|
21725308 |
2011 |
|
rs2395185
|
|
Carcinoma of lung
|
T |
0.710 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.
|
23143601 |
2012 |
|
rs3184504
|
|
Carcinoma of lung
|
C |
0.710 |
GeneticVariation
|
GWASCAT |
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
|
27197191 |
2016 |