Source: UNIPROT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs145518263
rs145518263
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function. 24055016

2013
dbSNP: rs145518263
rs145518263
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. 19608551

2009
dbSNP: rs483352912
rs483352912
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		0.800 GeneticVariation UNIPROT Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease. 23666529

2013
dbSNP: rs483352916
rs483352916
ADAM10
CUI: C0406811
Disease: Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura 		0.800 GeneticVariation UNIPROT Whole-exome sequencing identifies ADAM10 mutations as a cause of reticulate acropigmentation of Kitamura, a clinical entity distinct from Dowling-Degos disease. 23666529

2013
dbSNP: rs61751103
rs61751103
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function. 24055016

2013
dbSNP: rs61751103
rs61751103
ADAM10
CUI: C3810041
Disease: ALZHEIMER DISEASE 18
ALZHEIMER DISEASE 18 		0.800 GeneticVariation UNIPROT Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity. 19608551

2009
dbSNP: rs267604273
rs267604273
ADAM10
CUI: C1321872
Disease: Stage IV Skin Melanoma
Stage IV Skin Melanoma 		0.700 GeneticVariation UNIPROT