Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.900 GeneticVariation GWASDB Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. 21921092

2011
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		T 0.810 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		0.810 GeneticVariation GWASDB Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. 21921092

2011
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		A 0.800 GeneticVariation GWASDB Lung cancer susceptibility locus at 5p15.33. 18978790

2008
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. 18385738

2008
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1. 18385676

2008
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787

2008
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		C 0.800 GeneticVariation GWASDB Discovery and fine mapping of serum protein loci through transethnic meta-analysis. 23022100

2012
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.800 GeneticVariation GWASDB Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. 20418888

2010
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		0.800 GeneticVariation GWASDB Meta-analysis and imputation refines the association of 15q25 with smoking quantity. 20418889

2010
dbSNP: rs8040868
rs8040868
CHRNA3
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function 		T 0.800 GeneticVariation GWASDB Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. 23284291

2012
dbSNP: rs1051730
rs1051730
CHRNA3
CUI: C0028043
Disease: Nicotine Dependence
Nicotine Dependence 		T 0.790 GeneticVariation GWASDB A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. 18385739

2008
dbSNP: rs578776
rs578776
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.740 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs578776
rs578776
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.740 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.740 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.740 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs6495309
rs6495309
CHRNA3 ; CHRNB4
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.740 GeneticVariation GWASDB Common 5p15.33 and 6p21.33 variants influence lung cancer risk. 18978787

2008
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.730 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.730 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs12910984
rs12910984
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs12910984
rs12910984
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study. 19654303

2009
dbSNP: rs12914385
rs12914385
CHRNA3
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.710 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs8042374
rs8042374
CHRNA3
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.710 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012