Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1219648
rs1219648
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		G 0.800 GeneticVariation GWASCAT Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci. 27354352

2016
dbSNP: rs1219648
rs1219648
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		G 0.800 GeneticVariation GWASCAT A combined analysis of genome-wide association studies in breast cancer. 20872241

2011
dbSNP: rs1219648
rs1219648
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.800 GeneticVariation GWASCAT Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. 21263130

2011
dbSNP: rs1219648
rs1219648
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		G 0.800 GeneticVariation GWASCAT A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. 17529973

2007
dbSNP: rs2981582
rs2981582
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.800 GeneticVariation GWASCAT Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci. 27354352

2016
dbSNP: rs2981582
rs2981582
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.800 GeneticVariation GWASCAT Genome-wide association study identifies novel breast cancer susceptibility loci. 17529967

2007
dbSNP: rs3135753
rs3135753
FGFR2
CUI: C0018099
Disease: Gout
Gout 		T 0.800 GeneticVariation GWASCAT Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. 23263486

2013
dbSNP: rs2981578
rs2981578
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		C 0.790 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683

2017
dbSNP: rs2981578
rs2981578
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		C 0.790 GeneticVariation GWASCAT Genome-wide association study of breast cancer in the Japanese population. 24143190

2013
dbSNP: rs2420946
rs2420946
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.770 GeneticVariation GWASCAT Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk. 23544012

2013
dbSNP: rs2981579
rs2981579
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.740 GeneticVariation GWASCAT Genome-wide association study in East Asians identifies two novel breast cancer susceptibility loci. 27354352

2016
dbSNP: rs2981579
rs2981579
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.740 GeneticVariation GWASCAT Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer. 25751625

2015
dbSNP: rs2981579
rs2981579
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.740 GeneticVariation GWASCAT Large-scale genotyping identifies 41 new loci associated with breast cancer risk. 23535729

2013
dbSNP: rs2981579
rs2981579
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.740 GeneticVariation GWASCAT Genome-wide association study identifies five new breast cancer susceptibility loci. 20453838

2010
dbSNP: rs2981579
rs2981579
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		T 0.740 GeneticVariation GWASCAT A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). 19330030

2009
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		A 0.720 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs3750817
rs3750817
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		T 0.720 GeneticVariation GWASCAT In addition, rs3750817 in intron 2 of the fibroblast growth factor receptor 2 gene, which was reported to be associated with breast cancer susceptibility, was significantly replicated with P(combined) of 8.47 × 10(-8) with OR=1.22. 22951594

2012
dbSNP: rs2981575
rs2981575
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.710 GeneticVariation GWASCAT FGFR2 rs2981575 had the strongest association with breast cancer risk (per allele HR = 1.28, 95% CI 1.18-1.39, ). 21060860

2010
dbSNP: rs35054928
rs35054928
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		GC 0.710 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683

2017
dbSNP: rs10510097
rs10510097
FGFR2
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		T 0.700 GeneticVariation GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683

2017
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		A 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C2677123
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		A 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C1837315
Disease: COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		A 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C0346629
Disease: Malignant neoplasm of large intestine
Malignant neoplasm of large intestine 		A 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016
dbSNP: rs11200014
rs11200014
FGFR2
CUI: C0346163
Disease: Endometrioid carcinoma ovary
Endometrioid carcinoma ovary 		A 0.700 GeneticVariation GWASCAT Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations. 27197191

2016