Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs12593813
rs12593813
MAP2K5
CUI: C0035258
Disease: Restless Legs Syndrome
Restless Legs Syndrome 		G 0.810 GeneticVariation GWASCAT Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. 21779176

2011
dbSNP: rs12593813
rs12593813
MAP2K5
CUI: C0035258
Disease: Restless Legs Syndrome
Restless Legs Syndrome 		G 0.810 GeneticVariation GWASCAT Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. 17637780

2007
dbSNP: rs8028313
rs8028313
MAP2K5
CUI: C0028754
Disease: Obesity
Obesity 		C 0.800 GeneticVariation GWASCAT Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. 23563607

2013
dbSNP: rs11637027
rs11637027
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		G 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127

2018
dbSNP: rs16951001
rs16951001
MAP2K5
CUI: C0037369
Disease: Smoking
Smoking 		T 0.700 GeneticVariation GWASCAT Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. 30643258

2019
dbSNP: rs16951275
rs16951275
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584

2019
dbSNP: rs16951275
rs16951275
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625

2017
dbSNP: rs16951275
rs16951275
MAP2K5
CUI: C0037369
Disease: Smoking
Smoking 		T 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits. 28443625

2017
dbSNP: rs16951275
rs16951275
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively. 26961502

2016
dbSNP: rs16951275
rs16951275
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Genetic studies of body mass index yield new insights for obesity biology. 25673413

2015
dbSNP: rs2241423
rs2241423
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584

2019
dbSNP: rs2241423
rs2241423
MAP2K5
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement 		G 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
dbSNP: rs2241423
rs2241423
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		G 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
dbSNP: rs2241423
rs2241423
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.700 GeneticVariation GWASCAT The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study. 26426971

2015
dbSNP: rs2241423
rs2241423
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		G 0.700 GeneticVariation GWASCAT Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. 20935630

2010
dbSNP: rs28376010
rs28376010
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196

2017
dbSNP: rs3784710
rs3784710
MAP2K5
CUI: C1314691
Disease: Age at menarche
Age at menarche 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs3784710
rs3784710
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs3865018
rs3865018
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722

2019
dbSNP: rs4776970
rs4776970
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127

2018
dbSNP: rs4776970
rs4776970
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		T 0.700 GeneticVariation GWASCAT Genome-wide association study identifies 112 new loci for body mass index in the Japanese population. 28892062

2017
dbSNP: rs4776970
rs4776970
MAP2K5
CUI: C0455829
Disease: Waist Circumference
Waist Circumference 		A 0.700 GeneticVariation GWASCAT New genetic loci link adipose and insulin biology to body fat distribution. 25673412

2015
dbSNP: rs4776970
rs4776970
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index. 24861553

2014
dbSNP: rs4776970
rs4776970
MAP2K5
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.700 GeneticVariation GWASCAT Meta-analysis identifies common variants associated with body mass index in east Asians. 22344219

2012
dbSNP: rs7175517
rs7175517
MAP2K5
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement 		A 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017