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rs1024611
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CORONARY ARTERY DISEASE, DEVELOPMENT OF, IN HIV
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G |
0.700 |
CausalMutation
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CLINVAR |
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rs1024611
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SPINA BIFIDA, SUSCEPTIBILITY TO
|
G |
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
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rs1024611
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MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding)
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G |
0.700 |
SusceptibilityMutation
|
CLINVAR |
|
|
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rs1024611
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CORONARY ARTERY DISEASE, MODIFIER OF
|
G |
0.700 |
SusceptibilityMutation
|
CLINVAR |
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rs1024611
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Diabetes Mellitus, Non-Insulin-Dependent
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|
0.030 |
GeneticVariation
|
BEFREE |
The results of this study indicate that the use of 8 genetic polymorphisms associated with carbohydrate and lipid metabolism and type 2 diabetes [<i>PTGS2</i> (<i>COX2</i>) rs6681231, <i>FADS1</i> rs174550, <i>HNF1B</i> rs4430796, <i>ADIPOQ</i> rs266729, <i>IL18</i> rs187238, <i>CCL2</i> rs1024611, <i>HHEX</i> rs5015480 and <i>CDKN2A/2B</i> rs10811661] together with clinical risk factors (BMI and age) may significantly improve the prediction of GDM.
|
31299695 |
2019 |
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rs1024611
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Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
The objective of the present study is to evaluate the association, if any, of g.-2518A>G polymorphism (rs1024611) in MCP-1 gene in T2D cases with and without ESRD in the population of Punjab from North-West India.
|
25154422 |
2015 |
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rs1024611
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Ischemic stroke
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|
0.030 |
GeneticVariation
|
BEFREE |
Odds ratios (OR) with 95% confidence interval (CI) were used to evaluate the strength of associations between the MCP-1 A-2518G polymorphism (rs1024611) and IHD and IS susceptibilities.
|
25413568 |
2015 |
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rs1024611
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|
Ischemic stroke
|
|
0.030 |
GeneticVariation
|
BEFREE |
In summary, this study revealed no association of CCR2 rs1799864 SNP with IS, and a positive association between G minor allele of MCP1 rs1024611 SNP and IS in the Armenian population.
|
24083412 |
2014 |
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rs1024611
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Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our aim was to evaluate the frequency distribution of MCP1-2518 A/G (rs1024611) polymorphic variants in hemodialysis (HD) patients without or with type 2 diabetes in relation to serological markers of HBV infection.
|
24975639 |
2014 |
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rs1024611
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Ischemic stroke
|
|
0.030 |
GeneticVariation
|
BEFREE |
We have previously observed that genetic profiles determined by the combination of five functionally significant single nucleotide polymorphisms (SNPs) (rs1800795, rs5498, rs5361, rs1024611, and rs679620) of genes encoding prototypical inflammatory molecules are associated with history of ischemic stroke.
|
20622166 |
2010 |
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rs1024611
|
|
Gestational Diabetes
|
|
0.020 |
GeneticVariation
|
BEFREE |
The results of this study indicate that the use of 8 genetic polymorphisms associated with carbohydrate and lipid metabolism and type 2 diabetes [<i>PTGS2</i> (<i>COX2</i>) rs6681231, <i>FADS1</i> rs174550, <i>HNF1B</i> rs4430796, <i>ADIPOQ</i> rs266729, <i>IL18</i> rs187238, <i>CCL2</i> rs1024611, <i>HHEX</i> rs5015480 and <i>CDKN2A/2B</i> rs10811661] together with clinical risk factors (BMI and age) may significantly improve the prediction of GDM.
|
31299695 |
2019 |
|
rs1024611
|
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Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Besides, rs1024611 SNP was slightly correlated with increased DFUs susceptibility in patients with DM.
|
29995756 |
2018 |
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rs1024611
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Age related macular degeneration
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|
0.020 |
GeneticVariation
|
BEFREE |
Linear univariate and ANCOVA modeling was performed to show the interaction of rs1024611 with another SNP variant of CCL-2/CCR-2 (rs4586 and rs1799865) and impact of individual genotypes on CCL-2 expression in the context of AMD pathology.
|
29664944 |
2018 |
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rs1024611
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Gestational Diabetes
|
|
0.020 |
GeneticVariation
|
BEFREE |
In a multivariate regression analysis, age and BMI before pregnancy were independent significant predictors of a higher risk of GDM, while a lower number of G alleles <i>CCL2</i> rs1024611 was protective against GDM.
|
27472286 |
2017 |
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rs1024611
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Myocardial Infarction
|
|
0.020 |
GeneticVariation
|
BEFREE |
In order to find new informative predictors of myocardial infarction, we performed an analysis of genotype frequencies of polymorphic markers of SELE (rs2076059, 3832T > C), SELP (rs6131, S290 N), SELL (rs1131498, F206L), ICAM1 (rs5498, K469E), VCAM1 (rs3917010, c.928 + 420A > C), PECAM1 (rs668, V125L), VEGFA (rs35569394, -2549(18)I/D), CCL2 (rs1024611, -2518A > G), NOS3 (rs1799983, E298D), and DDAH1 (rs669173, c.303 + 30998A > G) genes in the group of Russian men with myocardial infarction (N = 315) and the control group of corresponding ethnicity, gender, and age (N = 286).
|
26662939 |
2016 |
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rs1024611
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Diabetes Mellitus
|
|
0.020 |
GeneticVariation
|
BEFREE |
Multivariate Cox regression analysis, taking into the account the recipient's sex, age and BMI, as well as the number of G alleles of the CCL2 rs1024611 polymorphism, revealed that this polymorphism is an independent risk factor for post-transplant diabetes.
|
26802601 |
2016 |
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rs1024611
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Age related macular degeneration
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|
0.020 |
GeneticVariation
|
BEFREE |
To evaluate the association of CC-cytokine ligand 2 CCL2-2518 (rs1024611) single nucleotide polymorphism, complement factor H (CFH Y402H) and their possible interaction in developing advanced age-related macular degeneration (AMD).
|
27316788 |
2016 |
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rs1024611
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Hepatitis B
|
|
0.020 |
GeneticVariation
|
BEFREE |
The aim of the study was to evaluate the distribution of MCP1-2518 A/G (rs1024611) polymorphic variants in patients on hemodialysis (HD) with respect to their responsiveness to hepatitis B vaccination.
|
24382482 |
2014 |
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rs1024611
|
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Hepatitis B
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our aim was to evaluate the frequency distribution of MCP1-2518 A/G (rs1024611) polymorphic variants in hemodialysis (HD) patients without or with type 2 diabetes in relation to serological markers of HBV infection.
|
24975639 |
2014 |
|
rs1024611
|
|
Myocardial Infarction
|
|
0.020 |
GeneticVariation
|
BEFREE |
Emerging evidence has shown that the common polymorphism (-2518A>G; rs1024611) in the MCP-1 gene may contribute to the risk of MI, but individually published studies showed inconclusive results.
|
24053559 |
2013 |
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rs1024611
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Aortic Aneurysm, Abdominal
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|
0.010 |
GeneticVariation
|
BEFREE |
Genotyping of rs1024611 in the MCP-1 gene was performed using TaqMan predesigned SNP genotyping assays in 27 patients with AAA (63% men, mean age of 71).
|
31201975 |
2020 |
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rs1024611
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Japanese Encephalitis
|
|
0.010 |
GeneticVariation
|
BEFREE |
TNFA rs1800629 A and CCR5 rs1799987 A alleles were associated with susceptibility while combination lacking TNFA rs1800629 A, CCR5 rs333 Δ32, and rs1799987 A alleles and CCL2 rs1024611 G/G genotype was associated with protection to JE.
|
31479868 |
2019 |
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rs1024611
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Non-alcoholic Fatty Liver Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to investigate the gene polymorphisms of MCP-1 (-2518 A/G) (rs1024611), CCR-2 (190 G/A) (rs1799864), ABCA1 (883 G/A) (rs4149313), and IL-17A (-197 G/A) (rs2275913) in obese Turkish children with non-alcoholic fatty liver disease.
|
29733805 |
2019 |
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rs1024611
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Neuroblastoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Dual-luciferase reporter assays were conducted in neuroblastoma cells to assess the promoter transcriptional activity of the rs1024611 variants (T>C) and the GRCh38.p12chr17:34252593 G>C alleles in CCL2.
|
30761072 |
2019 |
|
rs1024611
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Nasopharyngeal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, our findings suggested that rs1024611 at the MCP-1 promoter may be a risk factor for NPC.
|
30368911 |
2019 |