|
rs1799750
|
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
This examination, as the first study of its own kind in Iranian Turks, reported association between MMP-1 (rs1799750) -1607 2G/2G and MMP-3 (rs3025058) -1612 6A/6A genotypes and CAD risk in patients older than 50 years.
|
31356534 |
2019 |
|
rs1799750
|
|
Degenerative polyarthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
<b>Conclusion.</b> We systematically investigated the association between MMP-1-1607 (rs1799750) 1G/2G polymorphism and OA susceptibility; however, the results show no correlation.
|
30886066 |
2019 |
|
rs1799750
|
|
Coronary heart disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.
|
31356534 |
2019 |
|
rs1799750
|
|
Degenerative polyarthritis
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, this case-control study confirms that <i>MMP-1</i> gene rs1799750 polymorphism increases the risk of knee OA in Chinese Han population.
|
30177524 |
2018 |
|
rs1799750
|
|
Osteoarthritis, Knee
|
|
0.020 |
GeneticVariation
|
BEFREE |
The association between MMP-1 gene rs1799750 polymorphism and knee osteoarthritis risk.
|
30177524 |
2018 |
|
rs1799750
|
|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation
|
BEFREE |
Subgroup analyses showed that the rs1799750 was significantly associated with primary angle closure glaucoma under homozygote (OR = 2.23, 95% CI 1.03-4.83, p = 0.043) and allelic (OR = 1.61, 95% CI 1.07-2.42, P = 0.021) models, while it was significantly associated with primary open angle glaucoma (OR = 1.64, 95% CI 1.05-2.56, p = 0.030) and exfoliation glaucoma (OR = 1.42, 95% CI 1.02-1.97, p = 0.036) under recessive models.
|
27428613 |
2017 |
|
rs1799750
|
|
Coronary heart disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Thus, MMP-1 rs1799750 may be involved in the development of coexisting T2DM and CHD in the Han Chinese population.
|
27323171 |
2016 |
|
rs1799750
|
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
|
Coronary Artery Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
Significantly more C-2G (rs498186-rs1799750) haplotypes (p=0.001 after Bonferroni corrections) were found in CAD subjects.
|
25372932 |
2014 |
|
rs1799750
|
|
Carcinoma of bladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
|
Osteoarthritis, Knee
|
|
0.020 |
GeneticVariation
|
BEFREE |
The present study shows that MMP1 -1607 1G/2G (rs1799750) polymorphism might be a risk factor for knee osteoarthritis susceptibility in the Greek population.
|
24838892 |
2014 |
|
rs1799750
|
|
Malignant neoplasm of urinary bladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
The majority of the research described in the present mini-review proves that the genetic polymorphism in the MMP1 (rs1799750) is the most widely studied, and suggests that the rare genotype, 2G2G, of that gene might show increased susceptibility for bladder cancer, especially among smokers.
|
24635493 |
2014 |
|
rs1799750
|
|
Glaucoma, Primary Open Angle
|
|
0.020 |
GeneticVariation
|
BEFREE |
Our data suggest that the MMP1 rs1799750 (-1607 1G/2G) and MMP9 rs17576 polymorphisms might be of value for further study as potential gender-dependent risk factors for developing POAG and PACG, respectively, in Pakistan.
|
23441116 |
2013 |
|
rs1799750
|
|
Malignant neoplasm of urinary bladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1799750
|
|
Bladder Neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1799750
|
|
Carcinoma of bladder
|
|
0.020 |
GeneticVariation
|
BEFREE |
To elucidate genetic polymorphisms of the matrix metalloproteinases (MMPs) MMP1 (rs1799750), MMP2 (rs243865), MMP9 (rs3918242), MMP12 (rs2276109) and tissue inhibitors of MMPs (TIMPs) TIMP1 (rs2070584) and TIMP3 (rs9619311) genes that may be involved in susceptibility to bladder cancer (BC).
|
23819551 |
2013 |
|
rs1799750
|
|
Rotator cuff syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
In conclusion, a significant correlation was identified between the MMP-1 rs1799750 polymorphism</span> and RCT.
|
31652448 |
2019 |
|
rs1799750
|
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of MMP-1 (rs1799750)-1607 2G/2G and MMP-3 (rs3025058)-1612 6A/6A Genotypes With Coronary Artery Disease Risk Among Iranian Turks.
|
31356534 |
2019 |
|
rs1799750
|
|
Prostate carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Meta-analysis showed no associations between MMP1 rs1799750, MMP2 rs243865, or MMP7 rs11568818 and prostate cancer risk overall.
|
30464622 |
2018 |
|
rs1799750
|
|
Exudative age-related macular degeneration
|
|
0.010 |
GeneticVariation
|
BEFREE |
MMP1 rs1799750 1G/2G genotype was found to play a significant role in the development of eAMD at the age of less than 65 years.
|
29947568 |
2018 |
|
rs1799750
|
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
Meta-analysis showed no associations between MMP1 rs1799750, MMP2 rs243865, or MMP7 rs11568818 and prostate cancer risk overall.
|
30464622 |
2018 |
|
rs1799750
|
|
Rheumatic Heart Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that rs1799750 in MMP1 might be a risk factor for RHD in a Han population in Southern China, and individuals carrying the 2G/2G genotype are likely more susceptible to RHD.
|
29458338 |
2018 |
|
rs1799750
|
|
Exfoliation Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subgroup analyses showed that the rs1799750 was significantly associated with primary angle closure glaucoma under homozygote (OR = 2.23, 95% CI 1.03-4.83, p = 0.043) and allelic (OR = 1.61, 95% CI 1.07-2.42, P = 0.021) models, while it was significantly associated with primary open angle glaucoma (OR = 1.64, 95% CI 1.05-2.56, p = 0.030) and exfoliation glaucoma (OR = 1.42, 95% CI 1.02-1.97, p = 0.036) under recessive models.
|
27428613 |
2017 |
|
rs1799750
|
|
Acute Coronary Syndrome
|
|
0.010 |
GeneticVariation
|
BEFREE |
The aim of this study was to examine the association between MMP1-1607dupG (rs1799750) and MMP3-1171dupA (rs3025058) gene polymorphisms and acute coronary syndromes (ACS) in the form of unstable angina.
|
29044936 |
2017 |
|
rs1799750
|
|
Nasopharyngeal carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Subjects with MMP-1 rs1799750 polymorphism had an decreased N</span>PC risk (OR = 0.79; 95%CI, 0.69-0.91; P = 0.0007; I2 = 70%).
|
29096757 |
2017 |