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rs1799929
|
|
Acute leukemia
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association between rs1799929 and decreased AL risk was found in the co-dominant (OR 0.82, 95% CI 0.70-0.97), homozygous (OR 0.65, 95% CI 0.46-0.93), heterozygous (OR 0.71, 95% CI 0.51-1.00), and the recessive model (OR 0.68, 95% CI 0.49-0.94) in the Caucasian group.
|
30896661 |
2019 |
|
rs1799929
|
|
Male infertility
|
|
0.010 |
GeneticVariation
|
BEFREE |
This pilot study is the first (as far as we know) to reveal that polymorphisms of NAT2 (rs1799929, rs1799930) and GSTP1 (rs1138272, rs1695) are some novel genetic markers for susceptibility to idiopathic male infertility.
|
29505746 |
2018 |
|
rs1799929
|
|
Rectal Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
High fried red meat intake associated with NAT2-T341C, G590A, G857A, A845C, and C48</span>1T rapid acetylator allele determines a risk of 2.39 (P=.002), 2.39 (P=.002), 2.37 (P=.002), 2.28 (P=.004), and 2.51 (P=.001), respectively, for colon cancer, whereas in the case of rectal cancer, the risk increased to 7.55 (P<.001), 7.7 (P<.001), 7.83 (P<.001), 7.51 (P<.001), and 8.62 (P<.001), respectively.
|
27883249 |
2017 |
|
rs1799929
|
|
Colon Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
High fried red meat intake associated with NAT2-T341C, G590A, G857A, A845C, and C48</span>1T rapid acetylator allele determines a risk of 2.39 (P=.002), 2.39 (P=.002), 2.37 (P=.002), 2.28 (P=.004), and 2.51 (P=.001), respectively, for colon cancer, whereas in the case of rectal cancer, the risk increased to 7.55 (P<.001), 7.7 (P<.001), 7.83 (P<.001), 7.51 (P<.001), and 8.62 (P<.001), respectively.
|
27883249 |
2017 |
|
rs1799929
|
|
Malignant tumor of colon
|
|
0.010 |
GeneticVariation
|
BEFREE |
High fried red meat intake associated with NAT2-T341C, G590A, G857A, A845C, and C48</span>1T rapid acetylator allele determines a risk of 2.39 (P=.002), 2.39 (P=.002), 2.37 (P=.002), 2.28 (P=.004), and 2.51 (P=.001), respectively, for colon cancer, whereas in the case of rectal cancer, the risk increased to 7.55 (P<.001), 7.7 (P<.001), 7.83 (P<.001), 7.51 (P<.001), and 8.62 (P<.001), respectively.
|
27883249 |
2017 |
|
rs1799929
|
|
NAT2 polymorphism
|
|
0.010 |
GeneticVariation
|
BEFREE |
The NAT2 polymorphism was seen to be in Hardy-Weinberg equilibrium and showed significant genotypic as well as allelic association with phenytoin toxicity for NAT2*5A (481C>T) and NAT2*5C (803A>G).
|
22268821 |
2012 |
|
rs1799929
|
|
Oral Submucous Fibrosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Heterozygous XRCC3 codon 241 [OR 2.07 (1.05-4.06)], homozygous variant of NAT C481T [OR 2.81 (1.09-7.21)], and both heterozygous and homozygous variants of NAT codon 268 and 286 [OR 2.31 (1.20-4.45) and 4.98 (1.87-13.14), and 6.12 (2.75-13.62) and 2.65 (1.04-6.72)] individually influenced susceptibility to OSF in the population.
|
22092501 |
2012 |
|
rs1799929
|
|
Asthma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The C481T polymorphism was found to be significantly associated with asthma in our case-control studies at the genotype level (Armitage p = 0.00027).
|
16886893 |
2006 |
|
rs1799929
|
|
Slow acetylator due to N-acetyltransferase enzyme variant
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated three genetic variations, c.481C>T, c.590G>A (p.R197Q) and c.857G>A (p.G286E), of the NAT2 gene, which are known to result in a slow acetylator phenotype.
|
16827944 |
2006 |
|
rs1799929
|
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
The extraction method was combined with newly designed PCR-based assays for cancer susceptibility marker genes such as CYP1A1 (exon 7), CYP2E1 (Dra1, Rsa1), GSTM1 and NAT2 [NAT2*5A (C481T), NAT2*6A (G590A), NAT2*7A (G857A)].
|
9214613 |
1997 |
|
rs1799929
|
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
The extraction method was combined with newly designed PCR-based assays for cancer susceptibility marker genes such as CYP1A1 (exon 7), CYP2E1 (Dra1, Rsa1), GSTM1 and NAT2 [NAT2*5A (C481T), NAT2*6A (G590A), NAT2*7A (G857A)].
|
9214613 |
1997 |