Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.890 GeneticVariation GWASCAT Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension. 31055733

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		C 0.890 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.890 GeneticVariation GWASCAT Genome-wide analysis of genetic predisposition to Alzheimer's disease and related sex disparities. 30636644

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.890 GeneticVariation GWASCAT SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. 25027320

2014
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		C 0.890 GeneticVariation GWASCAT APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study. 23419831

2014
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.890 GeneticVariation GWASCAT Genome-wide association study of CSF biomarkers Abeta1-42, t-tau, and p-tau181p in the ADNI cohort. 21123754

2011
dbSNP: rs429358
rs429358
APOE
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		C 0.890 GeneticVariation CLINVAR

dbSNP: rs429358
rs429358
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		C 0.800 CausalMutation CLINVAR

dbSNP: rs429358
rs429358
APOE
CUI: C1863051
Disease: ALZHEIMER DISEASE 2
ALZHEIMER DISEASE 2 		0.800 GeneticVariation UNIPROT

dbSNP: rs429358
rs429358
APOE
CUI: C0020479
Disease: Hyperlipoproteinemia Type III
Hyperlipoproteinemia Type III 		0.730 GeneticVariation UNIPROT

dbSNP: rs429358
rs429358
APOE
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration 		0.720 GeneticVariation GWASCAT A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants. 26691988

2016
dbSNP: rs429358
rs429358
APOE
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.710 GeneticVariation GWASCAT Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension. 31055733

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0030567
Disease: Parkinson Disease
Parkinson Disease 		0.710 GeneticVariation GWASCAT Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms. 30957308

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0234985
Disease: Mental deterioration
Mental deterioration 		0.710 GeneticVariation GWASCAT Genetic architecture of age-related cognitive decline in African Americans. 28078323

2017
dbSNP: rs429358
rs429358
APOE
CUI: C0023980
Disease: Longevity
Longevity 		T 0.700 GeneticVariation GWASCAT A meta-analysis of genome-wide association studies identifies multiple longevity genes. 31413261

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0205682
Disease: Waist-Hip Ratio
Waist-Hip Ratio 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0011269
Disease: Dementia, Vascular
Dementia, Vascular 		C 0.700 GeneticVariation GWASCAT Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project. 31473137

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0205682
Disease: Waist-Hip Ratio
Waist-Hip Ratio 		T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease 		0.700 GeneticVariation GWASCAT GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study. 31065058

2019
dbSNP: rs429358
rs429358
APOE
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		T 0.700 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422

2018
dbSNP: rs429358
rs429358
APOE
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010

2018
dbSNP: rs429358
rs429358
APOE
CUI: C0085220
Disease: Cerebral Amyloid Angiopathy
Cerebral Amyloid Angiopathy 		0.700 GeneticVariation GWASCAT Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. 29458411

2018
dbSNP: rs429358
rs429358
APOE
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		0.700 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010

2018
dbSNP: rs429358
rs429358
APOE
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement 		T 0.700 GeneticVariation GWASCAT Genome-wide association study of habitual physical activity in over 377,000 UK Biobank participants identifies multiple variants including CADM2 and APOE. 29899525

2018
dbSNP: rs429358
rs429358
APOE
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018