Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		C 0.710 GeneticVariation GWASCAT Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730

2017
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.710 GeneticVariation BEFREE When conditioning on nine known functional variants and two deletions, the top two SNPs (rs56113850 in MEC and rs35755165 in TRICL) remained significantly associated with CYP2A6 activity in MEC and lung cancer in TRICL. 27488534

2016
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0007131
Disease: Non-Small Cell Lung Carcinoma
Non-Small Cell Lung Carcinoma 		C 0.700 GeneticVariation GWASCAT Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. 31326317

2019
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		C 0.700 GeneticVariation GWASCAT Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730

2017
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0149782
Disease: Squamous cell carcinoma of lung
Squamous cell carcinoma of lung 		C 0.700 GeneticVariation GWASCAT Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes. 28604730

2017
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C1519383
Disease: Smoking Behaviors
Smoking Behaviors 		T 0.700 GeneticVariation GWASCAT Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. 27488534

2016
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0037369
Disease: Smoking
Smoking 		T 0.700 GeneticVariation GWASCAT Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk. 27488534

2016
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0016529
Disease: Forced expiratory volume function
Forced expiratory volume function 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C3548479
Disease: response to bronchodilator
response to bronchodilator 		T 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245

2015
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE When conditioning on nine known functional variants and two deletions, the top two SNPs (rs56113850 in MEC and rs35755165 in TRICL) remained significantly associated with CYP2A6 activity in MEC and lung cancer in TRICL. 27488534

2016
dbSNP: rs56113850
rs56113850
CYP2A6
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE When conditioning on nine known functional variants and two deletions, the top two SNPs (rs56113850 in MEC and rs35755165 in TRICL) remained significantly associated with CYP2A6 activity in MEC and lung cancer in TRICL. 27488534

2016