|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Our findings demonstrated that VDR ApaI (rs7975232) and VDR BsmI (rs1544410) polymorphisms are correlated with susceptibility to PCOS in the Asian population and VDR TaqI (rs731236), VDR FokI (rs2228570), VDR Tru9I (rs757343) did not reveal a relationship with the PCOS susceptibility.
|
30764792 |
2019 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Present study investigated association between VDR gene BsmI A/G (rs1544410), ApaI A/C (rs7975232) and TaqI T/C (rs731236) single nucleotide polymorphisms and PCOS risk in South Indian women.
|
28868946 |
2018 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil.
|
29669566 |
2018 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Odds ratios (ORs) with 95% confidence interval (CIs) were calculated to assess the association between VDR Fok I C/T (rs10735810), BsmI A/G (rs1544410), ApaI A/C (rs7975232), and TaqI T/C (rs731236) polymorphisms and PCOS risk.
|
30687119 |
2018 |
|
rs731236
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Classic PCOS phenotype is not associated with deficiency of endogenous vitamin D and VDR gene polymorphisms rs731236 (TaqI), rs7975232 (ApaI), rs1544410 (BsmI), rs10735810 (FokI): a case-control study of lower Silesian women.
|
26422783 |
2015 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this study was to determine whether C to T base substitution within TaqI Vitamin D receptor (VDR) gene (rs731236) in exon 9 was a risk factor among patients with breast cancer.
|
28469103 |
2017 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of this study was to determine whether C to T base substitution within TaqI Vitamin D receptor (VDR) gene (rs731236) in exon 9 was a risk factor among patients with breast cancer.
|
28469103 |
2017 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The authors found that TC in rs731236, and TG in KY859868 single-nucleotide polymorphism showed significant distribution differences with an increased risk of breast cancer ( p < 0.05, odds ratio = 3.71, 95% confidence interval: 1.04-13.28 and p < 0.001, odds ratio = 7.05, 95% confidence interval: 2.02-24, respectively) compared with the wild-type TT genotype carriers in both single-nucleotide polymorphisms.
|
29022486 |
2017 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The authors found that TC in rs731236, and TG in KY859868 single-nucleotide polymorphism showed significant distribution differences with an increased risk of breast cancer ( p < 0.05, odds ratio = 3.71, 95% confidence interval: 1.04-13.28 and p < 0.001, odds ratio = 7.05, 95% confidence interval: 2.02-24, respectively) compared with the wild-type TT genotype carriers in both single-nucleotide polymorphisms.
|
29022486 |
2017 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our analysis suggests that VDR polymorphism rs731236 might be associated with breast cancer-specific mortality, and if our findings are confirmed in future bigger studies rs731236 might deserve consideration as a prognostic factor in clinical care of patients with breast cancer.
|
23300018 |
2013 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our analysis suggests that VDR polymorphism rs731236 might be associated with breast cancer-specific mortality, and if our findings are confirmed in future bigger studies rs731236 might deserve consideration as a prognostic factor in clinical care of patients with breast cancer.
|
23300018 |
2013 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
These results suggest that VDR rs2228570 and rs731236 polymorphisms are not related with the risk for MS, and did not confirm interaction between these VDR SNPs and HLADRB1 in the risk for MS.
|
23840333 |
2013 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, rs731236 TT VDR genotype modulates VDR expression and confers protection against MS in HLA-DRB1*15-positive individuals.
|
21664963 |
2011 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
No significant univariate associations between the polymorphisms, rs11574010 (Cdx-2A > G), rs10735810 (Fok1T > C), or rs731236 (Taq1C > T) and MS risk were observed.
|
19383647 |
2009 |
|
rs731236
|
|
Multiple Sclerosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
An association of two single-nucleotide polymorphisms (SNPs) of the vitamin D receptor (VDR) gene, Apal (rs7975232) and Taql (rs731236), with multiple sclerosis (MS) has been reported in a Caucasian population.
|
19758194 |
2009 |
|
rs731236
|
|
Malignant neoplasm of breast
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of the study was to determine whether four VDR gene single nucleotide polymorphisms (SNPs: rs1544410, rs731236, rs10735810 and rs4516035) are associated with breast cancer risk in Polish population.
|
18587672 |
2009 |
|
rs731236
|
|
Breast Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The aim of the study was to determine whether four VDR gene single nucleotide polymorphisms (SNPs: rs1544410, rs731236, rs10735810 and rs4516035) are associated with breast cancer risk in Polish population.
|
18587672 |
2009 |
|
rs731236
|
|
Gestational Diabetes
|
|
0.030 |
GeneticVariation
|
BEFREE |
Two VDR gene variants rs1544410 (OR = 2.03, 95% CI = 1.17-3.51 for CT versus CC) and rs731236 (OR = 2.42, 95% CI = 1.29-4.55 for GA versus AA) were significantly associated with the risk of GDM.
|
31341914 |
2019 |
|
rs731236
|
|
Nephrolithiasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The results demonstrated that there was no association found between the three SNPs (rs731236, rs7975232 and rs10735810) in the VDR gene and nephrolithiasis, whether in allele or genotype distribution.
|
29549381 |
2019 |
|
rs731236
|
|
Kidney Calculi
|
|
0.030 |
GeneticVariation
|
BEFREE |
Additionally, TaqI polymorphism (rs731236) was associated with a decreased risk of nephrolithiasis in the heterozygous model (OR = 0.77, CI 95% 0.63-0.94, Z p-value 0.010), and no overall association was observed with ApaI polymorphism (rs7975232).
|
31212049 |
2019 |
|
rs731236
|
|
Gestational Diabetes
|
|
0.030 |
GeneticVariation
|
BEFREE |
We aimed to investigate associations between VDR gene BsmI (rs15444410), ApaI (rs7975232), FokI (rs19735810), and TaqI (rs731236) single nucleotide polymorphisms (SNPs) and GDM.
|
31096931 |
2019 |
|
rs731236
|
|
Restless Legs Syndrome
|
|
0.030 |
GeneticVariation
|
BEFREE |
Moreover, after adjustment for age and sex, rs731236 of VDR were found associated with increased risk of RLS in the dominant model.
|
31063999 |
2019 |
|
rs731236
|
|
Kidney Calculi
|
|
0.030 |
GeneticVariation
|
BEFREE |
The results demonstrated that there was no association found between the three SNPs (rs731236, rs7975232 and rs10735810) in the VDR gene and nephrolithiasis, whether in allele or genotype distribution.
|
29549381 |
2019 |
|
rs731236
|
|
Colorectal Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In conclusion, minor allele of rs3025039, rs3212986, and rs712 polymorphisms increases the risk of CRC in the East Asian population, and heterozygote model of rs731236 polymorphism shows protective effect in the Middle East population.
|
31637880 |
2019 |
|
rs731236
|
|
Nephrolithiasis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Additionally, TaqI polymorphism (rs731236) was associated with a decreased risk of nephrolithiasis in the heterozygous model (OR = 0.77, CI 95% 0.63-0.94, Z p-value 0.010), and no overall association was observed with ApaI polymorphism (rs7975232).
|
31212049 |
2019 |