DisGeNET - a database of gene-disease associations

Source: GWASDB

Variant: rs780094 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs780094

GCKR

CUI:	C0011860
Disease:	Diabetes Mellitus, Non-Insulin-Dependent

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

22325160

2012

dbSNP:

rs780094

GCKR

CUI:	C0011860
Disease:	Diabetes Mellitus, Non-Insulin-Dependent

Diabetes Mellitus, Non-Insulin-Dependent

0.900

GeneticVariation

GWASDB

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

17463246

2007

dbSNP:

rs780094

GCKR

CUI:	C0524620
Disease:	Metabolic Syndrome X

Metabolic Syndrome X

0.830

GeneticVariation

GWASDB

Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.

22399527

2012

dbSNP:

rs780094

GCKR

CUI:	C0010068
Disease:	Coronary heart disease

Coronary heart disease

0.810

GeneticVariation

GWASDB

Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

21347282

2011

dbSNP:

rs780094

GCKR

CUI:	C0202236
Disease:	Triglycerides measurement

Triglycerides measurement

0.800

GeneticVariation

GWASDB

Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations.

23726366

2013

dbSNP:

rs780094

GCKR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.800

GeneticVariation

GWASDB

Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.

23505291

2013

dbSNP:

rs780094

GCKR

CUI:	C0003868
Disease:	Arthritis, Gouty

Arthritis, Gouty

0.800

GeneticVariation

GWASDB

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

23263486

2013

dbSNP:

rs780094

GCKR

CUI:	C0201925
Disease:	Calcium measurement

Calcium measurement

0.800

GeneticVariation

GWASDB

Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations.

24068962

2013

dbSNP:

rs780094

GCKR

CUI:	C0018099
Disease:	Gout

Gout

0.800

GeneticVariation

GWASDB

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

23263486

2013

dbSNP:

rs780094

GCKR

CUI:	C1305855
Disease:	Body mass index

Body mass index

0.800

GeneticVariation

GWASDB

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.

22581228

2012

dbSNP:

rs780094

GCKR

CUI:	C1445957
Disease:	Serum total cholesterol measurement

Serum total cholesterol measurement

0.800

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs780094

GCKR

CUI:	C0428568
Disease:	Fasting blood glucose measurement

Fasting blood glucose measurement

0.800

GeneticVariation

GWASDB

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.

22885924

2012

dbSNP:

rs780094

GCKR

CUI:	C0202236
Disease:	Triglycerides measurement

Triglycerides measurement

0.800

GeneticVariation

GWASDB

Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

23063622

2012

dbSNP:

rs780094

GCKR

CUI:	C0337438
Disease:	Glucose measurement

Glucose measurement

0.800

GeneticVariation

GWASDB

Human metabolic individuality in biomedical and pharmaceutical research.

21886157

2011

dbSNP:

rs780094

GCKR

CUI:	C0495706
Disease:	elevated blood glucose level

elevated blood glucose level

0.800

GeneticVariation

GWASDB

Human metabolic individuality in biomedical and pharmaceutical research.

21886157

2011

dbSNP:

rs780094

GCKR

CUI:	C0018099
Disease:	Gout

Gout

0.800

GeneticVariation

GWASDB

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

21768215

2011

dbSNP:

rs780094

GCKR

CUI:	C0003868
Disease:	Arthritis, Gouty

Arthritis, Gouty

0.800

GeneticVariation

GWASDB

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

21768215

2011

dbSNP:

rs780094

GCKR

CUI:	C0018099
Disease:	Gout

Gout

0.800

GeneticVariation

GWASDB

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

20884846

2010

dbSNP:

rs780094

GCKR

CUI:	C0003868
Disease:	Arthritis, Gouty

Arthritis, Gouty

0.800

GeneticVariation

GWASDB

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors.

20884846

2010

dbSNP:

rs780094

GCKR

CUI:	C0202239
Disease:	Uric acid measurement (procedure)

Uric acid measurement (procedure)

0.800

GeneticVariation

GWASDB

Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.

19503597

2009

dbSNP:

rs780094

GCKR

CUI:	C0202236
Disease:	Triglycerides measurement

Triglycerides measurement

0.800

GeneticVariation

GWASDB

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

19060911

2009

dbSNP:

rs780094

GCKR

CUI:	C0202117
Disease:	Low density lipoprotein cholesterol measurement

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASDB

Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.

18179892

2008

dbSNP:

rs780094

GCKR

CUI:	C0010346
Disease:	Crohn Disease

Crohn Disease

0.800

GeneticVariation

GWASDB

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

18587394

2008

dbSNP:

rs780094

GCKR

CUI:	C0202236
Disease:	Triglycerides measurement

Triglycerides measurement

0.800

GeneticVariation

GWASDB

Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

18193043

2008

dbSNP:

rs780094

GCKR

CUI:	C0201657
Disease:	C-reactive protein measurement

C-reactive protein measurement

0.800

GeneticVariation

GWASDB

Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.

18439548

2008