Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.900 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017
dbSNP: rs8050136
rs8050136
FTO
CUI: C0028754
Disease: Obesity
Obesity 		C 0.900 GeneticVariation GWASCAT Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. 21706003

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.900 GeneticVariation GWASCAT In the "obese-type 2 diabetes" scan, FTO variants had the strongest type 2 diabetes effect (rs8050136: relative risk [RR] 1.49 [95% CI 1.34-1.66], P = 1.3 x 10(-13)), with only weak evidence for TCF7L2 (rs7901695 RR 1.21 [1.09-1.35], P = 0.001). 19056611

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.900 GeneticVariation GWASCAT Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. 17463249

2007
dbSNP: rs8050136
rs8050136
FTO
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.900 GeneticVariation GWASCAT A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. 17463248

2007
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584

2019
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.800 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.800 GeneticVariation GWASCAT EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children. 24348519

2013
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.800 GeneticVariation GWASCAT In the combined analyses, a significant association was found between rs8050136, located in the first intron of the fat mass and obesity-associated (FTO) gene, and BMI (P = 4.97 × 10(-7)) and FFMI (P = 1.19 × 10(-7)). 21037115

2011
dbSNP: rs8050136
rs8050136
FTO
CUI: C1305855
Disease: Body mass index
Body mass index 		A 0.800 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005910
Disease: Body Weight
Body Weight 		A 0.800 GeneticVariation GWASCAT Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity. 19079260

2009
dbSNP: rs8050136
rs8050136
FTO
CUI: C0005845
Disease: Blood urea nitrogen measurement
Blood urea nitrogen measurement 		A 0.700 GeneticVariation GWASCAT A catalog of genetic loci associated with kidney function from analyses of a million individuals. 31152163

2019
dbSNP: rs8050136
rs8050136
FTO
CUI: C0202239
Disease: Uric acid measurement (procedure)
Uric acid measurement (procedure) 		A 0.700 GeneticVariation GWASCAT Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. 31578528

2019
dbSNP: rs8050136
rs8050136
FTO
CUI: C4049938
Disease: Physical Activity Measurement
Physical Activity Measurement 		A 0.700 GeneticVariation GWASCAT Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults. 28448500

2017
dbSNP: rs8050136
rs8050136
FTO
CUI: C1314691
Disease: Age at menarche
Age at menarche 		C 0.700 GeneticVariation GWASCAT Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. 25231870

2014
dbSNP: rs8050136
rs8050136
FTO
CUI: C0024117
Disease: Chronic Obstructive Airway Disease
Chronic Obstructive Airway Disease 		A 0.700 GeneticVariation GWASCAT Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. 21037115

2011