Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE Our meta-analysis suggested that a significant association existed between rs1799945 mutation and CHD, although this mutation was rare in Han Chinese. 23792061

2013

dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE After full adjustment, the odds ratio for coronary heart disease was 1.12 (95% CI, 0.92 to 1.37) for subjects with the compound heterozygous (C282Y/H63D) genotype relative to those with the wild-type/wild-type genotype. 20031541

2008

dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE Neither did we find an association between the H63D mutation and CHD risk (HR = 0.73, 95% CI = 0.43-1.24). 16968463

2006

dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE Haemochromatosis-causing mutations C282Y and H63D are not risk factors for coronary artery disease in Caucasians with type 2 diabetes. 15222129

2004

dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE We examined the relation between two HFE mutations (C282Y and H63D), indicators of iron homeostasis, and the prevalence of coronary heart disease in a large population of white adults. 12427496

2002

dbSNP: rs1799945
rs1799945
CUI: C0010068
Disease: Coronary heart disease
Coronary heart disease
0.060 GeneticVariation BEFREE To test whether genetic haemochromatosis is associated with increased atherosclerosis, we determined the prevalence of two mutations in the HFE gene related to haemochromatosis (845G-->A; Cys282Tyr. and 187 C-->G, His63Asp) in 265 consecutive patients with premature (<50 years of age) angiographically-proven atherosclerotic disease (coronary and/or peripheral), and in 272 healthy controls. 9753040

1998