rs699947
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
And VEGF-rs699947 polymorphism was also identified an increased risk of renal cell carcinoma (RCC) in allelic, heterozygote, dominant, homozygote, and recessive models.
|
29942264 |
2018 |
rs699947
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
In summary, our study showed evidence that the VEGF rs699947 polymorphism was obviously associated with an increased risk of bladder cancer and renal cell carcinoma, particularly in Asian population, while no significant association was observed in overall urologic neoplasms.
|
30195633 |
2018 |
rs699947
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
The pooled OR indicated that rs699947 polymorphism was significantly associated with RCC risk in all genetic models.
|
28356760 |
2017 |
rs699947
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our meta-analysis suggested that there may be a relationship between the VEGF rs2010963, rs3025039 and rs699947 polymorphisms and RCC susceptibility.
|
28562357 |
2017 |
rs1222213359
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Moreover, VEGF -1154G/A and -634C/G polymorphisms were found significantly associated with poor OS of RCC.
|
28489583 |
2017 |
rs1222213359
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In conclusion, our study presented the factors regarding the prognosis of RCC patients, and high platelet and neutrophil counts, low lymphocytes, and VEGF -2578C/A and -1154G/A polymorphisms were shown to be independent factors for a lower prognosis of RCC patients.
|
25062489 |
2014 |
rs1222213359
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
We investigated the associations of three polymorphisms (-2578C/A, -1154G/A, and -634C/G) in the VEGF gene with the clinicopathologic parameters and survival of 213 patients with RCC.
|
17287073 |
2007 |
rs2010963
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
As to rs1570360 or rs2010963, we did not observe any relationship between the two polymorphisms and RCC risk in our study.
|
28356760 |
2017 |
rs2010963
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our meta-analysis suggested that there may be a relationship between the VEGF rs2010963, rs3025039 and rs699947 polymorphisms and RCC susceptibility.
|
28562357 |
2017 |
rs2010963
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results indicate that VEGFA rs2010963 and VEGFR3 rs448012 are associated with risk of ccRCC.
|
25239121 |
2014 |
rs3025039
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
In the meanwhile, this study also demonstrated that the allele contrast model of rs3025039 polymorphism was likely to be associated with risk of RCC in the Asian population.
|
28356760 |
2017 |
rs3025039
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our meta-analysis suggested that there may be a relationship between the VEGF rs2010963, rs3025039 and rs699947 polymorphisms and RCC susceptibility.
|
28562357 |
2017 |
rs3025039
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.030 |
GeneticVariation
|
BEFREE |
Published data on the association between polymorphisms of vascular endothelial growth factor (e.g., -2578C/A [rs699947], -460T/C [rs833061], +405C/G [rs2010963], and +936C/T [rs3025039]) and the risk of renal cell carcinoma are ambiguous and controversial.
|
23073296 |
2013 |
rs10434
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our meta-analysis confirmed the fact that rs699947, rs3025039, and rs10434 polymorphisms were significantly relevant to elevated RCC risk.
|
28356760 |
2017 |
rs1570360
|
|
Conventional (Clear Cell) Renal Cell Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
The associations between five polymorphisms of VEGF (rs3025039, rs699947, rs10434, rs1570360, and rs2010963) and renal cell carcinoma (RCC) risk have been extensively investigated, but the currently available results are inconsistent and inconclusive.
|
28356760 |
2017 |