rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs169</span>5), and GSTT1null, especially when in conjunction with a cance</span>r family history and/or a smoking habit.
|
31107374 |
2019 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
GSTP1 Ile105Val was associated with increased lung function, reduced risk for lung cancer and tobacco-related cancer, and reduced all-cause mortality in the general population.
|
28739440 |
2017 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
In this study, a possible association of rs1695 GSTP1 polymorphisms, HR-HPV infection, and oral contraceptive use with cancer lesion development in women was investigated.
|
28829907 |
2017 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Associations of the glutathione S-transferase P1 Ile105Val genetic polymorphism with gynecological cancer susceptibility: a meta-analysis.
|
28410197 |
2017 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
For SNP rs1695 in the GSTP1 gene, a correlation with cancer disease stage was observed: a GG genotype is significantly more common in patients with PCa in the 3rd and 4th stage than 1st and 2nd (OR[95%CI] = 2.66[1.15-6.18], p = 0.02).
|
24610081 |
2014 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
Glutathione S-transferase P1 (GSTP1) gene Ile105Val polymorphism has been suggested to be involved in the development of cancer.
|
23765758 |
2013 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
GSTP1 Ile(105)Val gene polymorphism influences its expression in blood, regardless of cancer disease.
|
21669193 |
2011 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
There was no effect modification of glucosinolate intake and cancer risk by GSTA1 (G-52A) or GSTP1 (A313G) genotype, but serum glutathione S-transferase-alpha concentrations were inversely associated with prostate cancer.
|
20056632 |
2010 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
DNA from 143 cases reported to the Industrial Professional Associations (Berufsgenossenschaften) in Germany from 1996 to 2004, who had contracted urothelial cancer due to occupational exposure, and 196 patients from one Department of Surgery in Dortmund, without known malignancy in their medical history, were genotyped using real-time polymerase chain reaction (PCR) (LightCycler) in relation to GSTP1 A1578G (Ile105Val) polymorphism.
|
18569592 |
2008 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile105Val A-->G polymorphism was significantly associated with cancer risk (A/G+G/G: OR=0.60, 95%CI=0.39-0.94, p=0.02), and the effect of Val105 allele was largely confined to the subjects diagnosed earlier than 55 years old (A/G+G/G: OR,0.29; 95% CI, 0.09-0.87, p=0.03).
|
18199464 |
2008 |
rs1695
|
|
Primary malignant neoplasm
|
|
0.100 |
GeneticVariation
|
BEFREE |
The GSTP1 Ile105Val polymorphism was not found to be significantly associated with urothelial cancer susceptibility but it may be associated with myelosuppressive adverse events in M-VAC chemotherapy.
|
17593093 |
2007 |