Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
NOS3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE Pooled overall analyses showed that rs1799983 (dominant model: p = 0.01; recessive model: p = 0.007; allele model: p = 0.005), rs2070744 (recessive model: p = 0.004) and rs869109213 (recessive model: p < 0.0001; allele model: p = 0.02) polymorphisms were all significantly associated with individual susceptibility to cancer. 30582965

2019
dbSNP: rs1799983
rs1799983
NOS3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE The association between endothelial nitric oxide synthase (eNOS) polymorphisms (intron 4a/b, -786T>C and 894G>T) and cancer risk remains elusive. 26131841

2015
dbSNP: rs1799983
rs1799983
NOS3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE This meta-analysis suggests that G894T and 4a/b polymorphisms of NOS3 gene are not associated with increased or decreased risk of overall cancer. 25854385

2015
dbSNP: rs1799983
rs1799983
NOS3
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.040 GeneticVariation BEFREE This meta-analysis indicated that the eNOS T-786C polymorphism is associated with elevated cancer risk; the G894T polymorphism contributes to susceptibility to breast cancer and cancer generally in females; and the 4a/b polymorphism may be associated with prostate cancer risk. 25040995

2014