Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2853677
rs2853677
TERT
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.040 GeneticVariation BEFREE We observed that variant rs2853677 was strongly associated with lung cancer and leukemia risk with an odds ratio (OR) =1.8 (1.03-3.2 at 95% CI); p value (adjusted) = 0.03; odds ratio (OR) =2.9 (1.4-5.5.at 95% CI); p value (adjusted) = 0.002, respectively. 31126249

2019
dbSNP: rs2853677
rs2853677
TERT
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.040 GeneticVariation BEFREE Four polymorphisms exhibited prominent associations with lung cancer risk, including rs7726159 (OR = 1.34, 95%CI: 1.18-1.52, P = 7.78 × 10<sup>-6</sup> ), rs10054203 (OR = 1.29, 95%CI: 1.13-1.46, P = 1.37 × 10<sup>-4</sup> ), rs2736107 (OR = 1.28, 95%CI: 1.11-1.47, P = 5.14 × 10<sup>-4</sup> ), and rs2853677 (OR = 1.23, 95%CI: 1.08-1.39, P = 0.002). 30680798

2019
dbSNP: rs2853677
rs2853677
TERT
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.040 GeneticVariation BEFREE Our study indicated that rs10936599 (<i>TERC</i>) and rs10069690, rs2242652 and rs2853677 in <i>TERT</i> and haplotype "TA" of <i>TERT</i> were revealed as risk factors of lung cancer in a Chinese Han population. 29299136

2017
dbSNP: rs2853677
rs2853677
TERT
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.040 GeneticVariation BEFREE The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54). 27393504

2016