Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913250
rs121913250
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.720 GeneticVariation BEFREE Since hypoxic microenvironments select for tumor cells with diminished therapeutic response, we investigated whether hypoxia unequally increases resistance to 3-BrPA in wt p53 MelJuso melanoma harbouring (Q61L)-mutant NRAS and wt BRAF, C8161 melanoma with (G12D)-mutant KRAS (G464E)-mutant BRAF, and A549 lung carcinoma with a KRAS (G12S)-mutation. 27863474

2016
dbSNP: rs121913250
rs121913250
NRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.720 GeneticVariation BEFREE Direct sequencing of the melanoma revealed a rarely described NRAS mutation c.34G>T (G12C). 24335517

2014