Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1805006
rs1805006
MC1R
CUI: C0025202
Disease: melanoma
melanoma 		0.040 GeneticVariation BEFREE Melanoma risk increased with presence of any of the main MC1R variants: the SOR for each variant ranged from 1.47 (95%CI: 1.17-1.84) for V60L to 2.74 (1.53-4.89) for D84E. 24917043

2015
dbSNP: rs1805006
rs1805006
MC1R
CUI: C0025202
Disease: melanoma
melanoma 		0.040 GeneticVariation BEFREE In a multivariate model, however, only the D84E polymorphism influenced melanoma risk independently of the risk factors fair skin type, high nevus count and high age (P = 0.047). 17072629

2007
dbSNP: rs1805006
rs1805006
MC1R
CUI: C0025202
Disease: melanoma
melanoma 		0.040 GeneticVariation BEFREE We conclude that numerous melanocortin 1 receptor variants predispose to cutaneous melanoma and that possibly the Asp84Glu variant confers the highest risk. 11511307

2001
dbSNP: rs1805006
rs1805006
MC1R
CUI: C0025202
Disease: melanoma
melanoma 		0.040 GeneticVariation BEFREE The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma. 8894704

1996