Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2273535
rs2273535
AURKA
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.030 GeneticVariation BEFREE Our results indicate statistical evidence of an association between the STK15 F31I polymorphism and the increased risk of overall cancer in four genetic models: AA vs. TA+TT, AA vs. TT, AA vs. TA, and A vs. T. In a stratified analysis by cancer type, there was an increased risk of breast cancer in four genetic models: AA vs. TA+TT, AA vs. TT, AA vs. TA, and A vs. T, as well as esophageal cancer in two genetic models: AA vs. TA+TT and AA vs. TA. 24349361

2013
dbSNP: rs2273535
rs2273535
AURKA
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.030 GeneticVariation BEFREE We investigated the association between 2 nonsynonymous single nucleotide polymorphisms in the coding region of STK15, T91A (Phe31Ile) and G169A (Val57Ile), and clinical outcome of esophageal cancer treated with preoperative chemoradiation. 22213102

2012
dbSNP: rs2273535
rs2273535
AURKA
CUI: C0152018
Disease: Esophageal carcinoma
Esophageal carcinoma 		0.030 GeneticVariation BEFREE We have previously shown that the Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal cancer. 15271856

2004