DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Malignant neoplasm of ovary ×

Variant: rs5918 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs5918

ITGB3

CUI:	C1140680
Disease:	Malignant neoplasm of ovary

Malignant neoplasm of ovary

0.030

GeneticVariation

BEFREE

The ITGB3 Leu33Pro polymorphism does not modify breast or ovarian cancer risk in BRCA1 or BRCA2 mutation carriers.

19876733

2010

dbSNP:

rs5918

ITGB3

CUI:	C1140680
Disease:	Malignant neoplasm of ovary

Malignant neoplasm of ovary

0.030

GeneticVariation

BEFREE

Integrin beta3 Leu33Pro polymorphism increases BRCA1-associated ovarian cancer risk.

17220212

2007

dbSNP:

rs5918

ITGB3

CUI:	C1140680
Disease:	Malignant neoplasm of ovary

Malignant neoplasm of ovary

0.030

GeneticVariation

BEFREE

Integrin beta(3) Leu33Pro homozygotes have an increased risk of ovarian cancer.

16322334

2005