rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling in the brain: in good and bad times.
|
23570941 |
2013 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Characterising and predicting haploinsufficiency in the human genome.
|
20976243 |
2010 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Chronic DLL4 blockade induces vascular neoplasms.
|
20147986 |
2010 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis.
|
21092311 |
2010 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling controls liver development by regulating biliary differentiation.
|
19369401 |
2009 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching.
|
17296941 |
2007 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion.
|
17311993 |
2007 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling is essential for ventricular chamber development.
|
17336907 |
2007 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool.
|
17728344 |
2007 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
NOTCH2 mutations cause Alagille syndrome, a heterogeneous disorder of the notch signaling pathway.
|
16773578 |
2006 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling, brain development, and human disease.
|
15817497 |
2005 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles.
|
15923152 |
2005 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants.
|
15466160 |
2004 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.
|
15520367 |
2004 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Dosage-sensitive requirement for mouse Dll4 in artery development.
|
15466159 |
2004 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Regulation of Notch1 and Dll4 by vascular endothelial growth factor in arterial endothelial cells: implications for modulating arteriogenesis and angiogenesis.
|
12482957 |
2003 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1.
|
12574630 |
2003 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling is required for arterial-venous differentiation during embryonic vascular development.
|
11585794 |
2001 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Dll4, a novel Notch ligand expressed in arterial endothelium.
|
10837024 |
2000 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Notch signaling: cell fate control and signal integration in development.
|
10221902 |
1999 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
Neurogenic genes and vertebrate neurogenesis.
|
8794055 |
1996 |
rs1555393172
|
|
Multiple congenital anomalies
|
T |
0.700 |
GeneticVariation
|
CLINVAR |
The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands.
|
8756291 |
1996 |