Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
P25054 APC regulator of WNT signaling pathway 12 0.373 0.962 1.00 0.900 None 0.982 1 1 1990 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
P08253 matrix metallopeptidase 2 Enzyme 9 0.333 0.923 0.84 0.700 None 1.000 1 1 1996 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
P12830 cadherin 1 17 0.401 0.808 0.15 0.500 None 0.950 2 2 1999 2019
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
Q9NQB0 transcription factor 7 like 2 50 0.485 0.846 1.00 0.490 None 1.000 5 2 2002 2019
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
O60565 gremlin 1, DAN family BMP antagonist 11 0.508 0.808 0.47 0.430 None 1.000 5 3 2008 2020
Entrez Id: 894
Gene Symbol: CCND2
CCND2
P30279 cyclin D2 Enzyme modulator 16 0.477 0.808 0.99 0.420 None 1.000 4 3 2011 2019
Entrez Id: 4092
Gene Symbol: SMAD7
SMAD7
O15105 SMAD family member 7 Transcription factor 21 0.470 0.769 0.55 0.410 None 1.000 17 7 2007 2019
Entrez Id: 688
Gene Symbol: KLF5
KLF5
Q13887 Kruppel like factor 5 Nucleic acid binding 12 0.534 0.769 0.82 0.410 None 1.000 2 1 2008 2019
Entrez Id: 652
Gene Symbol: BMP4
BMP4
P12644 bone morphogenetic protein 4 Signaling 12 0.422 0.808 0.96 0.410 None 1.000 2 1 2008 2019
Entrez Id: 91653
Gene Symbol: BOC
BOC
Q9BWV1 BOC cell adhesion associated, oncogene regulated 14 0.666 0.423 1.7E-07 0.410 None 1.000 1 1 2018 2019
Entrez Id: 10714
Gene Symbol: POLD3
POLD3
Q15054 DNA polymerase delta 3, accessory subunit 12 0.631 0.462 1.00 0.400 None 1.000 6 3 2012 2019
Entrez Id: 143187
Gene Symbol: VTI1A
VTI1A
Q96AJ9 vesicle transport through interaction with t-SNAREs 1A Transporter 19 0.674 0.154 5.4E-04 0.400 None 1.000 6 4 2011 2019
Entrez Id: 85415
Gene Symbol: RHPN2
RHPN2
Q8IUC4 rhophilin Rho GTPase binding protein 2 Enzyme modulator 10 0.711 0.192 1.1E-07 0.400 None 1.000 6 4 2008 2019
Entrez Id: 64359
Gene Symbol: NXN
NXN
Q6DKJ4 nucleoredoxin 12 0.584 0.577 1.00 0.400 None 1.000 4 4 2014 2019
Entrez Id: 100289255
Gene Symbol: TMEM238L
TMEM238L
transmembrane protein 238 like 10 0.691 0.308 0.400 None 1.000 3 1 2019 2019
Entrez Id: 6578
Gene Symbol: SLCO2A1
SLCO2A1
Q92959 solute carrier organic anion transporter family member 2A1 Transporter 11 0.578 0.654 2.3E-13 0.400 None 1.000 3 3 2018 2019
Entrez Id: 9415
Gene Symbol: FADS2
FADS2
O95864 fatty acid desaturase 2 74 0.575 0.692 1.00 0.400 None 1.000 3 3 2014 2019
Entrez Id: 64399
Gene Symbol: HHIP
HHIP
Q96QV1 hedgehog interacting protein 21 0.550 0.654 0.95 0.400 None 1.000 2 2 2019 2019
Entrez Id: 4093
Gene Symbol: SMAD9
SMAD9
O15198 SMAD family member 9 Transcription factor 12 0.666 0.308 6.4E-05 0.400 None 1.000 2 2 2019 2019
Entrez Id: 57178
Gene Symbol: ZMIZ1
ZMIZ1
Q9ULJ6 zinc finger MIZ-type containing 1 40 0.588 0.615 1.00 0.400 None 1.000 1 1 2014 2019
Entrez Id: 1105
Gene Symbol: CHD1
CHD1
O14646 chromodomain helicase DNA binding protein 1 11 0.628 0.692 1.00 0.400 None 1.000 1 1 2019 2019
Entrez Id: 2237
Gene Symbol: FEN1
FEN1
P39748 flap structure-specific endonuclease 1 Enzyme 13 0.550 0.731 4.8E-05 0.400 None 1.000 1 1 2014 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3
P84022 SMAD family member 3 Transcription factor 53 0.415 0.923 0.80 0.400 None 1.000 1 1 2019 2019
Entrez Id: 1902
Gene Symbol: LPAR1
LPAR1
Q92633 lysophosphatidic acid receptor 1 G-protein coupled receptor 15 0.534 0.808 0.19 0.400 None 1.000 1 1 2019 2019
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 26 0.458 0.808 4.3E-54 0.400 None 1.000 1 1 2019 2019