Source: CLINVAR ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 84 0.236 0.962 0.53 0.800 None 0.977 1 22 1991 2020
Entrez Id: 5336
Gene Symbol: PLCG2
PLCG2 		P16885 phospholipase C gamma 2 Enzyme 2 0.588 0.808 1.00 0.700 None 0.929 1 2 2007 2020
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1 		O75533 splicing factor 3b subunit 1 Nucleic acid binding 8 0.511 0.731 1.00 0.500 None 0.974 1 4 2011 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 125 0.319 0.846 1.00 0.470 None 0.900 3 6 2007 2019
Entrez Id: 7514
Gene Symbol: XPO1
XPO1 		O14980 exportin 1 Receptor 5 0.504 0.692 1.00 0.440 None 1.000 1 2 2012 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		P01111 NRAS proto-oncogene, GTPase Enzyme modulator 37 0.390 0.808 0.49 0.130 None 1.000 1 2 1988 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 66 0.320 0.923 7.9E-04 0.130 None 1.000 1 1 1991 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 18 0.465 0.808 1.00 0.120 None 1.000 1 4 2011 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 71 0.378 0.885 8.0E-02 0.110 None 1.000 1 4 1991 2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		Q06124 protein tyrosine phosphatase non-receptor type 11 153 0.385 0.923 1.00 0.100 None 1.000 1 2 2016 2016
Entrez Id: 10992
Gene Symbol: SF3B2
SF3B2 		Q13435 splicing factor 3b subunit 2 9 0.780 0.308 1.00 0.100 None 1.000 1 2 2016 2016