Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.600 None 0.956 1 0 1999 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
P05231 interleukin 6 270 0.248 0.962 0.32 0.400 None 0.979 1 0 1996 2020
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
P01584 interleukin 1 beta 231 0.276 0.962 0.13 0.400 None 0.909 1 0 2000 2020
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
P01137 transforming growth factor beta 1 Signaling 179 0.287 0.962 3.7E-02 0.350 None 1.000 1 0 2002 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
P35354 prostaglandin-endoperoxide synthase 2 Enzyme 239 0.314 0.962 1.00 0.400 None 1.000 1 0 2004 2018
Entrez Id: 213
Gene Symbol: ALB
ALB
P02768 albumin Transporter 123 0.317 0.962 0.64 0.400 None 0.958 4 0 1998 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
P12821 angiotensin I converting enzyme Enzyme 101 0.328 0.923 1.0E-37 0.600 None 0.844 1 0 1994 2020
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
P42898 methylenetetrahydrofolate reductase 192 0.337 0.885 3.2E-10 0.500 None 0.938 3 0 1997 2019
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
P05362 intercellular adhesion molecule 1 57 0.364 0.962 3.5E-02 0.570 None 0.889 1 0 1999 2019
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
P35228 nitric oxide synthase 2 184 0.364 0.923 4.0E-15 0.560 None 1.000 1 0 1999 2018
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
P18510 interleukin 1 receptor antagonist 92 0.373 0.923 3.1E-02 0.400 None 0.944 1 0 1995 2018
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
P00441 superoxide dismutase 1 Enzyme 147 0.379 0.962 0.18 0.350 None 1.000 1 0 2000 2020
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
P05305 endothelin 1 Signaling 113 0.380 0.846 0.46 0.400 None 1.000 1 0 2003 2019
Entrez Id: 2147
Gene Symbol: F2
F2
P00734 coagulation factor II, thrombin Enzyme 61 0.415 0.885 1.1E-03 0.500 None 0.946 1 1 1995 2020
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 76 0.422 0.846 4.7E-02 0.490 strong 1.000 1 0 2002 2014
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
P00749 plasminogen activator, urokinase Enzyme 109 0.425 0.923 2.3E-06 0.310 None 1.000 1 0 2003 2019
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
P25101 endothelin receptor type A G-protein coupled receptor 28 0.426 0.885 0.99 0.510 None 1.000 1 0 2007 2019
Entrez Id: 28
Gene Symbol: ABO
ABO
P16442 ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase Enzyme 16 0.427 0.885 0.430 None 1.000 1 1 2009 2018
Entrez Id: 335
Gene Symbol: APOA1
APOA1
P02647 apolipoprotein A1 59 0.429 0.885 5.5E-04 0.380 None 1.000 1 0 2002 2019
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
Q9UM47 notch receptor 3 31 0.435 0.808 0.41 0.500 strong 0.973 1 2 1996 2020
Entrez Id: 2833
Gene Symbol: CXCR3
CXCR3
P49682 C-X-C motif chemokine receptor 3 G-protein coupled receptor 19 0.436 0.808 0.18 0.310 None 1.000 1 0 2000 2002
Entrez Id: 1471
Gene Symbol: CST3
CST3
P01034 cystatin C 55 0.436 0.808 3.9E-03 0.500 limited 1.000 0 0 1989 2020
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9
Q9UKV0 histone deacetylase 9 Epigenetic regulator 7 0.439 0.846 1.00 0.500 None 1.000 1 2 2012 2019
Entrez Id: 2153
Gene Symbol: F5
F5
P12259 coagulation factor V Enzyme 44 0.441 0.846 5.9E-15 0.500 None 0.971 1 1 1995 2016
Entrez Id: 4018
Gene Symbol: LPA
LPA
P08519 lipoprotein(a) Enzyme 15 0.444 0.769 6.6E-89 0.500 None 1.000 1 1 1989 2019