Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.600 Biomarker group CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.600 Biomarker group CTD_human The novel beta-blocker, carvedilol, provides neuroprotection in transient focal stroke. 10950380 2000
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3 		0.590 Biomarker group CTD_human Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators. 9445356 1998
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.570 Biomarker group CTD_human SO2 inhalation contributes to the development and progression of ischemic stroke in the brain. 20083630 2010
Entrez Id: 3674
Gene Symbol: ITGA2B
ITGA2B 		0.570 Biomarker group CTD_human Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators. 9445356 1998
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.560 Biomarker group CTD_human SO2 inhalation contributes to the development and progression of ischemic stroke in the brain. 20083630 2010
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA 		0.510 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		0.500 Biomarker group CTD_human We identified a new association for large vessel stroke within HDAC9 (encoding histone deacetylase 9) on chromosome 7p21.1 (including further replication in an additional 735 affected individuals and 28,583 controls) (rs11984041; combined P = 1.87 × 10(-11); odds ratio (OR) = 1.42, 95% confidence interval (CI) = 1.28-1.57). 22306652 2012
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3 		0.500 Biomarker group GENOMICS_ENGLAND Cysteine-sparing notch3 mutations: cadasil or cadasil variants? 19528524 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.500 Biomarker group CTD_human Na VPA-induced acute ischemic stroke in an epileptic patient with methylenetetrahydrofolate reductase gene polymorphism. 19646848 2009
Entrez Id: 1282
Gene Symbol: COL4A1
COL4A1 		0.500 Biomarker group GENOMICS_ENGLAND Clinical and brain MRI follow-up study of a family with COL4A1 mutation. 17938367 2007
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.500 Biomarker group CTD_human The MTHFR CT polymorphism confers a high risk for stroke in both homozygous and heterozygous T allele carriers with Type 2 diabetes. 16681562 2006
Entrez Id: 2153
Gene Symbol: F5
F5 		0.500 Biomarker group CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.500 Biomarker group CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
Entrez Id: 2147
Gene Symbol: F2
F2 		0.500 Biomarker group CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
Entrez Id: 4018
Gene Symbol: LPA
LPA 		0.500 Biomarker group CTD_human High plasma concentrations of lipoprotein(a) [Lp(a)], a covalent low-density lipoprotein-apolipoprotein(a) [apo(a)] complex, are associated with coronary heart disease and stroke. 10484779 1999
Entrez Id: 1471
Gene Symbol: CST3
CST3 		0.500 Biomarker group GENOMICS_ENGLAND
Entrez Id: 351
Gene Symbol: APP
APP 		0.490 Biomarker group GENOMICS_ENGLAND Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits. 20228223 2010
Entrez Id: 463
Gene Symbol: ZFHX3
ZFHX3 		0.480 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 54897
Gene Symbol: CASZ1
CASZ1 		0.440 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 28
Gene Symbol: ABO
ABO 		0.430 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3 		0.410 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 7482
Gene Symbol: WNT2B
WNT2B 		0.400 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 1021
Gene Symbol: CDK6
CDK6 		0.400 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018
Entrez Id: 5139
Gene Symbol: PDE3A
PDE3A 		0.400 Biomarker group CTD_human Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. 29531354 2018