Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF 		P01375 tumor necrosis factor Signaling 340 0.231 0.962 0.80 0.400 None 1.000 1 0 2008 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.600 None 0.957 2 0 1993 2020
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		P42771 Q8N726 cyclin dependent kinase inhibitor 2A 115 0.300 0.885 0.39 0.590 None 1.000 3 0 1996 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 130 0.303 0.885 1.00 0.400 None 1.000 2 0 1999 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.320 None 1.000 1 0 2007 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.520 None 1.000 2 0 1993 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3 		P40763 signal transducer and activator of transcription 3 Nucleic acid binding 138 0.320 0.923 1.00 0.400 None 1.000 1 0 2003 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.310 None 1.000 1 0 2006 2019
Entrez Id: 1437
Gene Symbol: CSF2
CSF2 		P04141 colony stimulating factor 2 Signaling 103 0.330 0.962 0.83 0.300 None 1.000 1 0 2007 2007
Entrez Id: 3558
Gene Symbol: IL2
IL2 		P60568 interleukin 2 75 0.336 0.885 0.48 0.350 None 1.000 1 0 2004 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC 		P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 91 0.344 0.923 1.00 0.590 None 1.000 2 0 1996 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 96 0.344 0.923 0.89 0.390 None 1.000 1 0 2005 2020
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		Q16236 nuclear factor, erythroid 2 like 2 Enzyme 89 0.357 0.885 3.6E-03 0.380 None 1.000 1 0 2010 2019
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 110 0.358 0.885 2.9E-02 0.360 None 1.000 1 0 2006 2018
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1 		P05121 serpin family E member 1 Enzyme modulator 44 0.359 0.885 4.4E-02 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1 		P01562 interferon alpha 1 28 0.371 0.923 0.340 None 1.000 1 0 2004 2019
Entrez Id: 324
Gene Symbol: APC
APC 		P25054 APC regulator of WNT signaling pathway 95 0.373 0.962 1.00 0.510 None 1.000 1 0 2016 2018
Entrez Id: 3082
Gene Symbol: HGF
HGF 		P14210 hepatocyte growth factor Enzyme 73 0.374 0.885 1.00 0.330 None 1.000 1 0 1994 2007
Entrez Id: 7015
Gene Symbol: TERT
TERT 		O14746 telomerase reverse transcriptase Enzyme 72 0.374 0.846 0.99 0.560 None 1.000 1 0 2007 2018
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		P09919 colony stimulating factor 3 168 0.377 0.885 0.38 0.300 None 1.000 1 0 1996 1996
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.310 None 1.000 5 0 2000 2007
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14 		Q16539 mitogen-activated protein kinase 14 Kinase 24 0.379 0.923 0.37 0.310 None 1.000 1 0 2007 2019
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1 		P09488 glutathione S-transferase mu 1 61 0.380 0.923 2.1E-03 0.310 None 1.000 1 0 2010 2011
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		P09601 heme oxygenase 1 137 0.381 0.923 9.7E-03 0.300 None 1.000 1 0 2006 2006
Entrez Id: 6513
Gene Symbol: SLC2A1
SLC2A1 		P11166 solute carrier family 2 member 1 Transporter 94 0.388 0.808 0.99 0.310 None 1.000 1 0 2016 2019