Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker disease CTD_human Genetic alterations in cancer knowledge system: analysis of gene mutations in mouse and human liver and lung tumors. 16410370 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.600 Biomarker disease CTD_human Abnormalities of the ARF-p53 pathway in primary angiosarcomas of the liver. 12378512 2002
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.590 Biomarker disease CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.590 Biomarker disease CTD_human Role of HSP90, CDC37, and CRM1 as modulators of P16(INK4A) activity in rat liver carcinogenesis and human liver cancer. 16317707 2005
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.590 Biomarker disease CTD_human Abnormalities of the ARF-p53 pathway in primary angiosarcomas of the liver. 12378512 2002
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.590 Biomarker disease CTD_human Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice. 11532874 2001
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.590 Biomarker disease CTD_human Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis. 8807143 1996
Entrez Id: 7015
Gene Symbol: TERT
TERT 		0.560 Biomarker disease CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
Entrez Id: 27232
Gene Symbol: GNMT
GNMT 		0.560 Biomarker disease CTD_human Deficiency of glycine N-methyltransferase results in deterioration of cellular defense to stress in mouse liver. 21137059 2010
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.550 Biomarker disease CTD_human We also found higher PPARα expression in the tumor area than adjacent areas and subsequently compared PPARα expression in four different hepatic cancer cell lines. 29134746 2018
Entrez Id: 5465
Gene Symbol: PPARA
PPARA 		0.550 Biomarker disease CTD_human Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. 20143881 2010
Entrez Id: 7039
Gene Symbol: TGFA
TGFA 		0.550 Biomarker disease CTD_human Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis. 8807143 1996
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.540 Biomarker disease CTD_human Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice. 12127304 2002
Entrez Id: 2272
Gene Symbol: FHIT
FHIT 		0.530 Biomarker disease CTD_human Alterations of the Fhit gene in hepatocellular carcinomas induced by N-nitrosodiethylamine in rats. 12112319 2002
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.520 Biomarker disease CTD_human Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development. 30556042 2018
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.520 Biomarker disease CTD_human Fish oil feeding reverses hepatomegaly and disrupted hepatic function due to the lack of FXR signaling. 29142166 2017
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.520 Biomarker disease CTD_human Suppression of autophagic flux by bile acids in hepatocytes. 24189133 2014
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.520 Biomarker disease CTD_human Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver. 23178280 2013
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4 		0.520 Biomarker disease CTD_human Mechanisms of STAT3 activation in the liver of FXR knockout mice. 24091600 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.520 Biomarker disease CTD_human Mutation analysis of K-ras-2 in liver angiosarcoma and adjacent nonneoplastic liver tissue from patients occupationally exposed to vinyl chloride. 12211074 2002
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.520 Biomarker disease CTD_human Ras gene mutations in vinyl chloride-induced liver tumours are carcinogen-specific but vary with cell type and species. 10629081 2000
Entrez Id: 440
Gene Symbol: ASNS
ASNS 		0.510 Biomarker disease CTD_human Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. 28108177 2017
Entrez Id: 324
Gene Symbol: APC
APC 		0.510 Biomarker disease CTD_human Whole-genome mutational landscape and characterization of noncoding and structural mutations in liver cancer. 27064257 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.400 Biomarker disease CTD_human Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan. 24183702 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.400 Biomarker disease CTD_human Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen. 21047994 2011