Source: BEFREE ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2475
Gene Symbol: MTOR
MTOR 		P42345 mechanistic target of rapamycin kinase Kinase 765 0.343 0.885 1.00 0.500 limited 1.000 14 0 2009 2019
Entrez Id: 10000
Gene Symbol: AKT3
AKT3 		Q9Y243 AKT serine/threonine kinase 3 Kinase 146 0.512 0.808 1.00 0.460 None 1.000 6 0 2012 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1277 0.292 0.923 1.00 0.450 None 1.000 5 0 2012 2018
Entrez Id: 7249
Gene Symbol: TSC2
TSC2 		P49815 TSC complex subunit 2 Enzyme modulator 276 0.439 0.808 1.00 0.130 None 1.000 3 0 2007 2019
Entrez Id: 7248
Gene Symbol: TSC1
TSC1 		Q92574 TSC complex subunit 1 248 0.440 0.808 1.00 0.130 None 1.000 3 0 2004 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		P60484 phosphatase and tensin homolog Enzyme 983 0.305 0.923 0.26 0.130 None 1.000 3 0 2014 2018
Entrez Id: 9681
Gene Symbol: DEPDC5
DEPDC5 		O75140 DEP domain containing 5, GATOR1 subcomplex subunit Nucleic acid binding 47 0.631 0.538 0.12 0.130 None 1.000 3 0 2015 2019
Entrez Id: 6009
Gene Symbol: RHEB
RHEB 		Q15382 Ras homolog, mTORC1 binding Enzyme modulator 47 0.631 0.577 0.98 0.110 None 1.000 1 0 2019 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB 		P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1077 0.322 0.885 1.00 0.050 None 1.000 5 0 2012 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1 		P31749 AKT serine/threonine kinase 1 Kinase 1011 0.311 0.962 0.98 0.050 None 1.000 5 0 2013 2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1087 0.320 0.885 1.4E-06 0.050 None 1.000 5 0 2012 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1105 0.319 0.885 1.00 0.050 None 1.000 5 0 2012 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		P35222 catenin beta 1 1156 0.303 0.885 1.00 0.030 None 1.000 3 0 2005 2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		P24385 cyclin D1 Enzyme modulator 748 0.344 0.923 0.89 0.030 None 1.000 3 0 2005 2007
Entrez Id: 100380873
Gene Symbol: FECD3
FECD3 		Corneal dystrophy, Fuchs endothelial, 3 11 0.769 0.385 0.030 None 1.000 3 0 2014 2019
Entrez Id: 100188278
Gene Symbol: FECD2
FECD2 		corneal dystrophy, Fuchs endothelial 2 6 0.821 0.154 0.010 None 1.000 1 0 2019 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		P23560 brain derived neurotrophic factor Signaling 852 0.345 0.923 0.66 0.010 None 1.000 1 0 2004 2004
Entrez Id: 7471
Gene Symbol: WNT1
WNT1 		P04628 Wnt family member 1 Signaling 183 0.495 0.769 0.33 0.010 None 1.000 1 0 2005 2005
Entrez Id: 8131
Gene Symbol: NPRL3
NPRL3 		Q12980 NPR3 like, GATOR1 complex subunit 22 0.678 0.385 0.19 0.010 None 1.000 1 0 2019 2019
Entrez Id: 6194
Gene Symbol: RPS6
RPS6 		P62753 ribosomal protein S6 Nucleic acid binding 103 0.547 0.692 0.98 0.010 None 1.000 1 0 2019 2019
Entrez Id: 8840
Gene Symbol: CCN4
CCN4 		O95388 cellular communication network factor 4 Signaling 100 0.554 0.692 6.4E-07 0.010 None 1.000 1 0 2005 2005
Entrez Id: 6559
Gene Symbol: SLC12A3
SLC12A3 		P55017 solute carrier family 12 member 3 Transporter 170 0.493 0.808 3.0E-32 0.010 None 1.000 1 0 2004 2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1043 0.314 0.962 1.00 0.010 None 1.000 1 0 2019 2019
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		P14136 glial fibrillary acidic protein 411 0.421 0.885 1.5E-06 0.010 None 1.000 1 0 2007 2007
Entrez Id: 3897
Gene Symbol: L1CAM
L1CAM 		P32004 L1 cell adhesion molecule 197 0.475 0.769 1.00 0.010 None 1.000 1 0 1997 1997