Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP
P05067 amyloid beta precursor protein Enzyme modulator 485 0.422 0.846 4.7E-02 0.400 None 1.000 36 0 1997 2020
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
P10636 microtubule associated protein tau 469 0.446 0.923 6.0E-03 0.370 None 1.000 12 1 2002 2019
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1
P49768 presenilin 1 Enzyme 369 0.469 0.846 0.97 0.350 None 1.000 7 0 2008 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1193 0.320 0.923 1.00 0.320 None 1.000 3 0 2008 2014
Entrez Id: 9365
Gene Symbol: KL
KL
Q9UEF7 klotho Enzyme 332 0.448 0.769 2.2E-04 0.310 None 1.000 3 0 2014 2017
Entrez Id: 4012
Gene Symbol: LNPEP
LNPEP
Q9UIQ6 leucyl and cystinyl aminopeptidase Enzyme 174 0.514 0.731 1.00 0.310 None 1.000 2 0 2001 2011
Entrez Id: 2558
Gene Symbol: GABRA5
GABRA5
P31644 gamma-aminobutyric acid type A receptor subunit alpha5 Ion channel 73 0.621 0.385 0.91 0.310 None 1.000 2 0 2010 2017
Entrez Id: 6855
Gene Symbol: SYP
SYP
P08247 synaptophysin Transporter 243 0.481 0.808 0.92 0.310 None 1.000 2 0 2011 2019
Entrez Id: 43
Gene Symbol: ACHE
ACHE
P22303 acetylcholinesterase (Cartwright blood group) Enzyme 418 0.445 0.885 1.00 0.310 None 1.000 2 0 2008 2017
Entrez Id: 1128
Gene Symbol: CHRM1
CHRM1
P11229 cholinergic receptor muscarinic 1 G-protein coupled receptor 68 0.653 0.577 0.99 0.310 None 1.000 2 0 2011 2017
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
P31645 solute carrier family 6 member 4 Transporter 440 0.429 0.808 0.25 0.300 None 1.000 2 0 2008 2008
Entrez Id: 3363
Gene Symbol: HTR7
HTR7
P34969 5-hydroxytryptamine receptor 7 G-protein coupled receptor 103 0.592 0.500 4.5E-02 0.300 None 1.000 1 0 2011 2011
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
P14416 dopamine receptor D2 G-protein coupled receptor 437 0.436 0.846 0.75 0.300 None 1.000 1 0 2011 2011
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 229 0.522 0.846 0.20 0.300 None 1.000 1 0 2003 2003
Entrez Id: 3362
Gene Symbol: HTR6
HTR6
P50406 5-hydroxytryptamine receptor 6 G-protein coupled receptor 57 0.626 0.500 1.9E-04 0.300 None 1.000 1 0 2010 2010
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
P04440 major histocompatibility complex, class II, DP beta 1 Immune response 324 0.453 0.923 5.3E-10 0.300 None 1.000 1 0 2004 2004
Entrez Id: 57030
Gene Symbol: SLC17A7
SLC17A7
Q9P2U7 solute carrier family 17 member 7 Transporter 79 0.636 0.308 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 596
Gene Symbol: BCL2
BCL2
P10415 BCL2 apoptosis regulator Signaling 1456 0.291 0.885 0.56 0.300 None 1.000 1 0 2007 2007
Entrez Id: 5966
Gene Symbol: REL
REL
Q04864 REL proto-oncogene, NF-kB subunit Transcription factor 90 0.579 0.692 1.00 0.300 None 1.000 1 0 2010 2010
Entrez Id: 5071
Gene Symbol: PRKN
PRKN
O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 409 0.431 0.846 6.9E-07 0.300 None 1.000 1 0 2003 2003
Entrez Id: 28964
Gene Symbol: GIT1
GIT1
Q9Y2X7 GIT ArfGAP 1 56 0.647 0.538 1.00 0.300 None 1.000 1 0 2011 2011
Entrez Id: 56848
Gene Symbol: SPHK2
SPHK2
Q9NRA0 sphingosine kinase 2 Kinase 140 0.546 0.731 1.3E-07 0.300 None 1.000 1 0 2014 2014
Entrez Id: 6531
Gene Symbol: SLC6A3
SLC6A3
Q01959 solute carrier family 6 member 3 Transporter 373 0.453 0.885 1.00 0.300 None 1.000 1 0 2008 2008
Entrez Id: 2925
Gene Symbol: GRPR
GRPR
P30550 gastrin releasing peptide receptor G-protein coupled receptor 85 0.595 0.538 0.22 0.300 None 1.000 1 0 2007 2007
Entrez Id: 57084
Gene Symbol: SLC17A6
SLC17A6
Q9P2U8 solute carrier family 17 member 6 Transporter 43 0.678 0.500 0.16 0.300 None 1.000 1 0 2011 2011