Source: CURATED ×
Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53 		P04637 tumor protein p53 Transcription factor 232 0.236 0.962 0.53 0.460 None 1.000 0 1 1995 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		P01116 KRAS proto-oncogene, GTPase Enzyme modulator 164 0.320 0.923 7.9E-04 0.410 None < 0.001 0 1 2019 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 98 0.292 0.923 1.00 0.410 None 1.000 0 3 2018 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		P04626 erb-b2 receptor tyrosine kinase 2 Kinase 83 0.328 0.923 6.0E-03 0.400 None 0.917 0 0 1990 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		P03372 estrogen receptor 1 Nuclear receptor 113 0.324 0.962 1.00 0.380 None 0.875 0 0 2002 2015
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1 		P38398 BRCA1 DNA repair associated Enzyme 57 0.367 0.923 9.2E-29 0.330 None 1.000 0 0 2004 2008
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		P01112 HRas proto-oncogene, GTPase Enzyme modulator 120 0.378 0.885 8.0E-02 0.310 None 1.000 0 0 1996 1996
Entrez Id: 2625
Gene Symbol: GATA3
GATA3 		P23771 GATA binding protein 3 30 0.415 0.846 0.90 0.310 None 1.000 0 0 2016 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 115 0.319 0.846 1.00 0.310 None < 0.001 0 0 2019 2019
Entrez Id: 6926
Gene Symbol: TBX3
TBX3 		O15119 T-box transcription factor 3 Transcription factor 22 0.525 0.769 0.99 0.300 None 0 0
Entrez Id: 695
Gene Symbol: BTK
BTK 		Q06187 Bruton tyrosine kinase Kinase 10 0.464 0.808 1.00 0.300 None 0 0
Entrez Id: 6602
Gene Symbol: SMARCD1
SMARCD1 		Q96GM5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 Nucleic acid binding 11 0.695 0.385 1.00 0.300 None 0 0
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2 		P51587 BRCA2 DNA repair associated Nucleic acid binding 56 0.379 0.846 2.4E-25 0.300 None 0 0
Entrez Id: 9611
Gene Symbol: NCOR1
NCOR1 		O75376 nuclear receptor corepressor 1 Transcription factor 22 0.597 0.731 1.00 0.300 None 0 0
Entrez Id: 9175
Gene Symbol: MAP3K13
MAP3K13 		O43283 mitogen-activated protein kinase kinase kinase 13 Kinase 5 0.743 0.192 0.80 0.300 None 0 0
Entrez Id: 8924
Gene Symbol: HERC2
HERC2 		O95714 HECT and RLD domain containing E3 ubiquitin protein ligase 2 9 0.568 0.692 1.00 0.300 None 0 0
Entrez Id: 8821
Gene Symbol: INPP4B
INPP4B 		O15327 inositol polyphosphate-4-phosphatase type II B 17 0.573 0.577 0.55 0.300 None 0 0
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		Q14790 caspase 8 Enzyme 58 0.404 0.923 3.7E-06 0.300 None 0 0
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1 		Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 21 0.507 0.731 6.2E-17 0.300 None 0 0
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		Q92560 BRCA1 associated protein 1 Enzyme 108 0.454 0.731 0.99 0.300 None 0 0
Entrez Id: 8289
Gene Symbol: ARID1A
ARID1A 		O14497 AT-rich interaction domain 1A 48 0.455 0.846 1.00 0.300 None 0 0
Entrez Id: 79728
Gene Symbol: PALB2
PALB2 		Q86YC2 partner and localizer of BRCA2 33 0.485 0.769 3.0E-19 0.300 None 0 0
Entrez Id: 6416
Gene Symbol: MAP2K4
MAP2K4 		P45985 mitogen-activated protein kinase kinase 4 Kinase 12 0.559 0.692 1.00 0.300 None 0 0
Entrez Id: 5925
Gene Symbol: RB1
RB1 		P06400 RB transcriptional corepressor 1 Nucleic acid binding 65 0.444 0.885 1.00 0.300 None 0 0
Entrez Id: 57492
Gene Symbol: ARID1B
ARID1B 		Q8NFD5 AT-rich interaction domain 1B 15 0.503 0.846 1.00 0.300 None 0 0