| Gene | UniProt | Gene Full Name | Protein Class | N. diseases g | DSI g | DPI g | pLI | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
P02649 | apolipoprotein E | 115 | 0.338 | 0.962 | 1.9E-03 | 0.440 | None | 0.800 | 1 | 0 | 2006 | 2019 | |||||
|
O00206 | toll like receptor 4 | 80 | 0.321 | 0.962 | 4.6E-09 | 0.420 | None | 1.000 | 1 | 0 | 2017 | 2019 | |||||
|
P06280 | galactosidase alpha | 15 | 0.537 | 0.769 | 1.00 | 0.420 | strong | 1.000 | 1 | 0 | 2004 | 2015 | |||||
|
P01019 | angiotensinogen | Enzyme modulator | 146 | 0.367 | 0.923 | 5.0E-08 | 0.400 | None | 1.000 | 1 | 0 | 1997 | 2019 | ||||
|
P12821 | angiotensin I converting enzyme | Enzyme | 101 | 0.328 | 0.923 | 1.0E-37 | 0.400 | None | 0.947 | 1 | 0 | 1997 | 2019 | ||||
|
P37231 | peroxisome proliferator activated receptor gamma | Nuclear receptor | 110 | 0.358 | 0.885 | 2.9E-02 | 0.400 | None | 1.000 | 1 | 0 | 2017 | 2017 | ||||
|
P01588 | erythropoietin | 90 | 0.381 | 0.885 | 1.1E-02 | 0.330 | None | 0.750 | 1 | 0 | 2005 | 2015 | |||||
|
P05305 | endothelin 1 | Signaling | 113 | 0.380 | 0.846 | 0.46 | 0.320 | None | 1.000 | 1 | 0 | 1994 | 2019 | ||||
|
Q9NPH5 | NADPH oxidase 4 | Enzyme | 19 | 0.471 | 0.885 | 5.8E-20 | 0.310 | None | 1.000 | 1 | 0 | 2013 | 2018 | ||||
|
P48735 | isocitrate dehydrogenase (NADP(+)) 2 | 83 | 0.434 | 0.808 | 0.88 | 0.310 | None | 1.000 | 1 | 0 | 2016 | 2017 | |||||
|
P08473 | membrane metalloendopeptidase | Enzyme | 35 | 0.407 | 0.808 | 1.5E-18 | 0.310 | None | 1.000 | 1 | 0 | 1999 | 2017 | ||||
|
P01579 | interferon gamma | 167 | 0.288 | 0.962 | 0.47 | 0.300 | None | 1.000 | 2 | 0 | 1986 | 1994 | |||||
|
P01308 | insulin | 157 | 0.445 | 0.923 | 0.30 | 0.300 | None | 1.000 | 2 | 0 | 1996 | 1998 | |||||
|
P48357 | leptin receptor | Signaling | 79 | 0.433 | 0.808 | 0.99 | 0.300 | None | 1.000 | 1 | 0 | 2018 | 2018 | ||||
|
P01563 | interferon alpha 2 | 170 | 0.442 | 0.885 | 0.300 | None | 1.000 | 1 | 0 | 1987 | 1987 | ||||||
|
Q07973 | cytochrome P450 family 24 subfamily A member 1 | Enzyme | 25 | 0.518 | 0.692 | 3.2E-23 | 0.300 | None | 1.000 | 1 | 0 | 1994 | 1994 | ||||
|
P13498 | cytochrome b-245 alpha chain | 19 | 0.520 | 0.769 | 8.9E-06 | 0.300 | None | 1.000 | 1 | 0 | 2013 | 2013 |