Gene: KRAS ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Prognostic value of the KRAS G12V mutation in 841 surgically resected Caucasian lung adenocarcinoma cases. 26372703 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer. 23548132 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK. 22897852 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. 22235099 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR KRAS(G12V) enhances proliferation and initiates myelomonocytic differentiation in human stem/progenitor cells via intrinsic and extrinsic pathways. 21169357 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissues. 20926413 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Effect of simvastatin on cetuximab resistance in human colorectal cancer with KRAS mutations. 21398618 2011
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR A synthetic lethal interaction between K-Ras oncogenes and Cdk4 unveils a therapeutic strategy for non-small cell lung carcinoma. 20609353 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR KRAS mutation analysis in ovarian samples using a high sensitivity biochip assay. 19358724 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Correlation of clinical features with the mutational status of GM-CSF signaling pathway-related genes in juvenile myelomonocytic leukemia. 19047918 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations. 19396835 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Mutations of FLT3, NRAS, KRAS, and PTPN11 are frequent and possibly mutually exclusive in high hyperdiploid childhood acute lymphoblastic leukemia. 17910045 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer. 18594010 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. 19029981 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Frequency and distinctive spectrum of KRAS mutations in never smokers with lung adenocarcinoma. 18794081 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Spontaneous improvement of hematologic abnormalities in patients having juvenile myelomonocytic leukemia with specific RAS mutations. 17332249 2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Cardio-facio-cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype-phenotype relationships and overlap with Costello syndrome. 17704260 2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Erlotinib for frontline treatment of advanced non-small cell lung cancer: a phase II study. 17062680 2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 GeneticVariation disease CLINVAR Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome. 16474404 2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR Somatic PTPN11 mutations in childhood acute myeloid leukaemia. 15842656 2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. 15696205 2005
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.700 CausalMutation disease CLINVAR BRAF and RAS mutations in human lung cancer and melanoma. 12460918 2002