Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 Biomarker group CTD_human Transcriptional profiling endometrial carcinomas microdissected from DES-treated mice identifies changes in gene expression associated with estrogenic tumor promotion. 16804899 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 Biomarker group CTD_human Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis in recombinant mice. 16402032 2006
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 Biomarker group CTD_human Akt activity in endometrial cancer cells: regulation of cell survival through cIAP-1. 12888921 2003
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.600 Biomarker group CTD_human PTEN1 is frequently mutated in primary endometrial carcinomas. 9326929 1997
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.400 Biomarker group CTD_human Activating ESR1 mutations in hormone-resistant metastatic breast cancer. 24185510 2013
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.400 Biomarker group CTD_human Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase. 21936542 2011
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.390 Biomarker group CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.360 Biomarker group CTD_human The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture. 17380299 2007
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.340 Biomarker group CTD_human Genomic Aberrations that Activate D-type Cyclins Are Associated with Enhanced Sensitivity to the CDK4 and CDK6 Inhibitor Abemaciclib. 29232554 2017
Entrez Id: 2100
Gene Symbol: ESR2
ESR2 		0.330 Biomarker group CTD_human The endometrial cancer cell lines Ishikawa and HEC-1A, and the control cell line HIEEC, differ in expression of estrogen biosynthetic and metabolic genes, and in androstenedione and estrone-sulfate metabolism. 25437045 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.320 Biomarker group CTD_human Familial endometrial cancer in female carriers of MSH6 germline mutations. 10508506 1999
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.320 Biomarker group CTD_human Mutations of the E-cadherin gene in human gynecologic cancers. 8075649 1994
Entrez Id: 4609
Gene Symbol: MYC
MYC 		0.310 Biomarker group CTD_human Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers. 26656844 2016
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		0.310 Biomarker group CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
Entrez Id: 1583
Gene Symbol: CYP11A1
CYP11A1 		0.310 Biomarker group CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
Entrez Id: 6770
Gene Symbol: STAR
STAR 		0.310 Biomarker group CTD_human Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer. 23200943 2013
Entrez Id: 2033
Gene Symbol: EP300
EP300 		0.310 Biomarker group CTD_human Exome sequencing of serous endometrial tumors identifies recurrent somatic mutations in chromatin-remodeling and ubiquitin ligase complex genes. 23104009 2012
Entrez Id: 3206
Gene Symbol: HOXA10
HOXA10 		0.310 Biomarker group CTD_human Expression of HOXA10 in endometrial hyperplasia and adenocarcinoma and regulation by sex hormones in vitro. 21670700 2011
Entrez Id: 8743
Gene Symbol: TNFSF10
TNFSF10 		0.310 Therapeutic group CTD_human The multikinase inhibitor Sorafenib induces apoptosis and sensitises endometrial cancer cells to TRAIL by different mechanisms. 20071162 2010
Entrez Id: 1645
Gene Symbol: AKR1C1
AKR1C1 		0.310 Biomarker group CTD_human AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer. 16338060 2006
Entrez Id: 8644
Gene Symbol: AKR1C3
AKR1C3 		0.310 Biomarker group CTD_human AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer. 16338060 2006
Entrez Id: 255488
Gene Symbol: RNF144B
RNF144B 		0.300 Biomarker group CTD_human Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation. 29724995 2018
Entrez Id: 3927
Gene Symbol: LASP1
LASP1 		0.300 Biomarker group CTD_human Long non-coding RNA LINC00672 contributes to p53 protein-mediated gene suppression and promotes endometrial cancer chemosensitivity. 28232485 2017
Entrez Id: 8204
Gene Symbol: NRIP1
NRIP1 		0.300 Biomarker group CTD_human The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis. 27348297 2016
Entrez Id: 6495
Gene Symbol: SIX1
SIX1 		0.300 Biomarker group CTD_human SIX1 Oncoprotein as a Biomarker in a Model of Hormonal Carcinogenesis and in Human Endometrial Cancer. 27259717 2016