|
TNFRSF1A
|
0.090 |
Biomarker
|
disease |
BEFREE |
Fifteen autoinflammation/immune-related genes (ADA2-CARD14-IL10RA-LPIN2-MEFV-MVK-NLRC4-NLRP12-NLRP3-NOD2-PLCG2-PSTPIP1-SLC29A3-TMEM173-TNFRSF1A) were used to screen 196 subjects from adult/pediatric clinics, each with an initial clinical suspicion of one or more sAID diagnosis with the exclusion of typical familial Mediterranean fever (FMF) patients.
|
30783801 |
2019 |
|
TNFRSF1A
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
Further, specific blockade of TNFR1 or activation of TNFR2 could provide substantial protection against FMF pathologies.
|
30457980 |
2019 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Autoinflammatory syndromes include familial Mediterranean fever (FMF), due to mutations in the MEFV gene, and tumor necrosis factor receptor-associated periodic syndrome (TRAPS), due to mutations in the TNFRSF1A gene.
|
20074469 |
2010 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Role of the R92Q TNFRSF1A mutation in patients with familial Mediterranean fever.
|
20506103 |
2010 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The HPFs include familial Mediterranean fever (FMF), hyperimmunoglobulinemia D with periodic fever syndrome (HIDS), TNF receptor-associated syndrome (TRAPS), and cryopyrinopathies, which are attributable to mutations of the MEFV, MVK, TNFRSF1A, and CIAS1 genes, respectively.
|
19877056 |
2009 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
It would be interesting to evaluate the role of the R92Q mutation in TNFRSF1A in patients of Mediterranean origin with FMF unresponsive to colchicine.
|
17949559 |
2008 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Among hereditary fevers characterized by recurrent attacks of fever and organ localized inflammation, familial Mediterranean fever (FMF), and tumour necrosis factor receptor superfamily 1A (TNFRSF1A) receptor associated periodic syndrome (TRAPS) are diseases with identified genes that can be associated with renal amyloidosis of the AA type.
|
12105243 |
2002 |
|
TNFRSF1A
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
TNFRSF1A mutations were found in patients of various ethnic origins, including those at risk for familial Mediterranean fever (FMF): Armenians, Sephardic Jews, and especially Arabs from Maghreb.
|
12209523 |
2002 |
|
TNFRSF1A
|
0.090 |
Biomarker
|
disease |
BEFREE |
A mutation search was performed in the MEFV (Mediterranean fever) and tumor necrosis factor receptor 1 (TNFR1 or TNFRSF1A) genes causing familial Mediterranean fever (FMF) and tumor necrosis factor receptor-associated periodic syndrome (TRAPS), respectively.
|
11318938 |
2001 |