Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.600 Biomarker group CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046 2013
Entrez Id: 100048912
Gene Symbol: CDKN2B-AS1
CDKN2B-AS1
0.420 Biomarker group CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845 2016
Entrez Id: 11321
Gene Symbol: GPN1
GPN1
0.410 Biomarker group CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845 2016
Entrez Id: 10319
Gene Symbol: LAMC3
LAMC3
0.410 Biomarker group CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845 2016
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
0.410 Biomarker group CTD_human Oral cancer was associated with two new regions, 2p23.3 (rs6547741, GPN1) and 9q34.12 (rs928674, LAMC3), and with known cancer-related loci-9p21.3 (rs8181047, CDKN2B-AS1) and 5p15.33 (rs10462706, CLPTM1L). 27749845 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.400 Biomarker group CTD_human Promoter region hypermethylation and mRNA expression of MGMT and p16 genes in tissue and blood samples of human premalignant oral lesions and oral squamous cell carcinoma. 24991542 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
0.400 Biomarker group CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046 2013
Entrez Id: 125
Gene Symbol: ADH1B
ADH1B
0.400 Biomarker group CTD_human Multiple ADH genes are associated with upper aerodigestive cancers. 18500343 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.400 Biomarker group CTD_human Elevated expression of cyclooxygenase (COX)-2 in oral squamous cell carcinoma--evidence for COX-2 induction by areca quid ingredients in oral keratinocytes. 12969226 2003
Entrez Id: 4255
Gene Symbol: MGMT
MGMT
0.350 Biomarker group CTD_human Promoter region hypermethylation and mRNA expression of MGMT and p16 genes in tissue and blood samples of human premalignant oral lesions and oral squamous cell carcinoma. 24991542 2014
Entrez Id: 1834
Gene Symbol: DSPP
DSPP
0.340 Biomarker group CTD_human DSPP-silencing in OSC2 cell decreased salient hallmarks of oral tumorigenesis and provides the first functional evidence of a potential key role for DSPP in oral cancer biology. 21103065 2010
Entrez Id: 126
Gene Symbol: ADH1C
ADH1C
0.340 Biomarker group CTD_human Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde. 15138216 2004
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
0.330 Biomarker group CTD_human Focal adhesion kinase knockdown in carcinoma-associated fibroblasts inhibits oral squamous cell carcinoma metastasis via downregulating MCP-1/CCL2 expression. 25199511 2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.330 Biomarker group CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046 2013
Entrez Id: 3606
Gene Symbol: IL18
IL18
0.330 Biomarker group CTD_human Impact of interleukin-18 polymorphisms -607A/C and -137G/C on oral cancer occurrence and clinical progression. 24349532 2013
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.330 Biomarker group CTD_human Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model. 19435901 2009
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1
0.320 Biomarker group CTD_human Finally, patients with oral cancer who had at least 1 T allele of ICAM-1 rs5491 or 1 G allele of rs281432 were at lower risk of developing an advanced clinical stage (III/IV) (p<0.05), compared to those patients with AA or CC homozygotes. 24069166 2013
Entrez Id: 3158
Gene Symbol: HMGCS2
HMGCS2
0.310 Biomarker group CTD_human HMGCS2 enhances invasion and metastasis via direct interaction with PPARα to activate Src signaling in colorectal cancer and oral cancer. 27816970 2017
Entrez Id: 10397
Gene Symbol: NDRG1
NDRG1
0.310 Biomarker group CTD_human Prognostic significance of NDRG1 expression in oral and oropharyngeal squamous cell carcinoma. 22972152 2012
Entrez Id: 1410
Gene Symbol: CRYAB
CRYAB
0.310 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.310 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 301
Gene Symbol: ANXA1
ANXA1
0.310 Biomarker group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.310 Therapeutic group CTD_human Proteomics of buccal squamous cell carcinoma: the involvement of multiple pathways in tumorigenesis. 15274141 2004
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.310 Therapeutic group CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
0.310 Biomarker group CTD_human Inhibition of oral cancer cell growth by adenovirusMnSOD plus BCNU treatment. 12543247 2003