Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 AlteredExpression disease BEFREE Tubulocystic carcinoma and collecting duct carcinoma did not express cytokeratin 7 differentially. 19390420 2009
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 Biomarker disease BEFREE The cell lines had the characteristic immunophenotype of CDC (high molecular weight cytokeratin-+ve/cytokeratin 7-+ve/vimentin-+ve). 19154479 2009
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 Biomarker disease CTD_human Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma. 16927643 2006
Entrez Id: 3855
Gene Symbol: KRT7
KRT7 		0.320 Biomarker disease CTD_human Differential protein profiling in renal-cell carcinoma. 15108329 2004
Entrez Id: 7030
Gene Symbol: TFE3
TFE3 		0.310 Biomarker disease BEFREE Cases with ASPSCR1-TFE3, SFPQ-TFE3, PRCC-TFE3, and NONO-TFE3 gene fusion showed a wide variability in morphologic features, including invasive tubulopapillary pattern simulating collecting duct carcinoma, extensive calcification and ossification, and overlapping and high columnar cells with nuclear grooves mimicking tall cell variant of papillary thyroid carcinoma. 29713041 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.310 Biomarker disease CTD_human Spectrum of diverse genomic alterations define non-clear cell renal carcinoma subtypes. 25401301 2015
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human NADPH oxidase NOX4 supports renal tumorigenesis by promoting the expression and nuclear accumulation of HIF2α. 24755467 2014
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Integrated molecular analysis of clear-cell renal cell carcinoma. 23797736 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.310 Biomarker disease CTD_human Integrated molecular analysis of clear-cell renal cell carcinoma. 23797736 2013
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells. 21097529 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. 22138691 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.310 Biomarker disease CTD_human Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma. 22138691 2011
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Bilateral renal-cell carcinoma associated with an acquired VHL mutation and long-term trichloroethylene exposure. 19473641 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.310 Biomarker disease CTD_human Synergy of interferon-alpha and 5-fluorouracil in human renal cell carcinoma requires p53 activity. 17275163 2007
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference? 15177666 2004
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Role of transforming growth factor-alpha in von Hippel--Lindau (VHL)(-/-) clear cell renal carcinoma cell proliferation: a possible mechanism coupling VHL tumor suppressor inactivation and tumorigenesis. 11171960 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.310 Biomarker disease CTD_human HER-2/neu is expressed in human renal cell carcinoma at heterogeneous levels independently of tumor grading and staging and can be recognized by HLA-A2.1-restricted cytotoxic T lymphocytes. 10897039 2000
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma. 10340905 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.310 Biomarker disease BEFREE LOH in p53 was observed in 0/8 cases of cRCC compared to 18.7% in CDC. 9625847 1998
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 GeneticVariation disease BEFREE The findings indicate that CDC and cRCC share certain genetic alterations, including frequent deletion of the vHL gene. 9625847 1998
Entrez Id: 7428
Gene Symbol: VHL
VHL 		0.310 Biomarker disease CTD_human Renal cell carcinomas in trichloroethene (TRI) exposed persons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene. 9137812 1997
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.310 Biomarker disease BEFREE The high incidence of c-erbB-2 oncogene amplification in CDC further characterizes this tumor as a separate entity from renal cell carcinoma, and shows some genetic characteristics in common with transitional cell carcinoma. 9186368 1997
Entrez Id: 7030
Gene Symbol: TFE3
TFE3 		0.310 Biomarker disease CTD_human
Entrez Id: 3566
Gene Symbol: IL4R
IL4R 		0.300 Biomarker disease CTD_human Polymorphism rs4787951 in IL-4R contributes to the increased risk of renal cell carcinoma in a Chinese population. 30472377 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Biomarker disease CTD_human Adiponectin gene polymorphisms and obesity increase the susceptibility to arsenic-related renal cell carcinoma. 29723618 2018