Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3630
Gene Symbol: INS
INS 		0.500 Biomarker phenotype CTD_mouse Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects. 18056790 2008
Entrez Id: 3630
Gene Symbol: INS
INS 		0.500 Therapeutic phenotype CTD_human Reversible impairment of renal function associated with enalapril in a diabetic patient. 9861226 1998
Entrez Id: 3630
Gene Symbol: INS
INS 		0.500 Biomarker phenotype CTD_human Reversible impairment of renal function associated with enalapril in a diabetic patient. 9861226 1998
Entrez Id: 3630
Gene Symbol: INS
INS 		0.500 Therapeutic phenotype CTD_human Iatrogenic neonatal hypertrophic cardiomyopathy. 8660453 1996
Entrez Id: 3630
Gene Symbol: INS
INS 		0.500 Biomarker phenotype CTD_human Iatrogenic neonatal hypertrophic cardiomyopathy. 8660453 1996
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.400 Biomarker phenotype CTD_human Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects. 18056790 2008
Entrez Id: 3643
Gene Symbol: INSR
INSR 		0.400 Biomarker phenotype HPO
Entrez Id: 2215
Gene Symbol: FCGR3B
FCGR3B 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 9332
Gene Symbol: CD163
CD163 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A 		0.300 Biomarker phenotype CTD_human Improvement of hyperglycemia in a murine model of insulin resistance and high glucose- and inflammasome-mediated IL-1β expressions in macrophages by silymarin. 29753610 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker phenotype CTD_human Increased susceptibility to troglitazone-induced mitochondrial permeability transition in type 2 diabetes mellitus model rat. 29743445 2018
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.300 Biomarker phenotype CTD_human PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal. 29367455 2018
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic phenotype CTD_human A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. 29991592 2018
Entrez Id: 958
Gene Symbol: CD40
CD40 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 3684
Gene Symbol: ITGAM
ITGAM 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker phenotype CTD_human Coagonist of glucagon-like peptide-1 and glucagon receptors ameliorates kidney injury in murine models of obesity and diabetes mellitus. 29988851 2018
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker phenotype CTD_human A collagen domain-derived short adiponectin peptide activates APPL1 and AMPK signaling pathways and improves glucose and fatty acid metabolisms. 29991592 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.300 Biomarker phenotype CTD_human Expression of macrophage genes within skeletal muscle correlates inversely with adiposity and insulin resistance in humans. 29035695 2018
Entrez Id: 8660
Gene Symbol: IRS2
IRS2 		0.300 Biomarker phenotype CTD_human Resveratrol treatment restores peripheral insulin sensitivity in diabetic mice in a sirt1-independent manner. 25808216 2015
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker phenotype CTD_human Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models. 24384915 2014
Entrez Id: 3159
Gene Symbol: HMGA1
HMGA1 		0.300 Biomarker phenotype CTD_human A polymorphism of HMGA1 is associated with increased risk of metabolic syndrome and related components. 23512162 2013
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.300 Therapeutic phenotype CTD_human Increased vulnerability to β-cell destruction and diabetes in mice lacking NAD(P)H:quinone oxidoreductase 1. 23458895 2013
Entrez Id: 177
Gene Symbol: AGER
AGER 		0.300 Biomarker phenotype CTD_human Graptopetalum paraguayense and resveratrol ameliorates carboxymethyllysine (CML)-induced pancreas dysfunction and hyperglycemia. 24036142 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP 		0.300 Biomarker phenotype CTD_human Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. 21561152 2011