Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Therapeutic phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Biomarker phenotype CTD_human Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. 21269288 2011
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 AlteredExpression phenotype BEFREE Decreased serum BDNF levels in patients with epileptic and psychogenic nonepileptic seizures. 20921514 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Therapeutic phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Biomarker phenotype CTD_human Effects of PRI-2191--a low-calcemic analog of 1,25-dihydroxyvitamin D3 on the seizure-induced changes in brain gene expression and immune system activity in the rat. 15781040 2005
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Therapeutic phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.310 Biomarker phenotype CTD_human Induction of brain derived neurotrophic factor mRNA by seizures in neonatal and juvenile rat brain. 9073163 1997
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
0.300 Biomarker phenotype CTD_human IL-6 knockout mice are protected from cocaine-induced kindling behaviors; possible involvement of JAK2/STAT3 and PACAP signalings. 29673861 2018
Entrez Id: 7249
Gene Symbol: TSC2
TSC2
0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
0.300 Biomarker phenotype CTD_human Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. 28215400 2017
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD
0.300 Biomarker phenotype CTD_human Protein kinase Cδ mediates trimethyltin-induced neurotoxicity in mice in vivo via inhibition of glutathione defense mechanism. 25895139 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.300 Therapeutic phenotype CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 43
Gene Symbol: ACHE
ACHE
0.300 Biomarker phenotype CTD_human HI-6 assisted catalytic scavenging of VX by acetylcholinesterase choline binding site mutants. 27083141 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
0.300 Biomarker phenotype CTD_human A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model. 27469509 2016
Entrez Id: 3785
Gene Symbol: KCNQ2
KCNQ2
0.300 Biomarker phenotype CTD_human KCNQ2 encephalopathy: Features, mutational hot spots, and ezogabine treatment of 11 patients. 27602407 2016
Entrez Id: 6904
Gene Symbol: TBCD
TBCD
0.300 Biomarker phenotype CTD_human Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy. 27666370 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL
0.300 Therapeutic phenotype CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 249
Gene Symbol: ALPL
ALPL
0.300 Biomarker phenotype CTD_human Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation. 27466191 2016
Entrez Id: 2166
Gene Symbol: FAAH
FAAH
0.300 Therapeutic phenotype CTD_human Enhancement of endocannabinoid signaling protects against cocaine-induced neurotoxicity. 25933444 2015
Entrez Id: 3737
Gene Symbol: KCNA2
KCNA2
0.300 Biomarker phenotype CTD_human De novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy. 25751627 2015
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 348
Gene Symbol: APOE
APOE
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 54886
Gene Symbol: PLPPR1
PLPPR1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 4504
Gene Symbol: MT3
MT3
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013
Entrez Id: 7779
Gene Symbol: SLC30A1
SLC30A1
0.300 Biomarker phenotype CTD_human Expression profiles of hippocampal regenerative sprouting-related genes and their regulation by E-64d in a developmental rat model of penicillin-induced recurrent epilepticus. 23266720 2013