Gene: APP ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs63751039
rs63751039
APP
0.790 GeneticVariation UNIPROT

dbSNP: rs193922916
rs193922916
APP
A 0.740 CausalMutation CLINVAR

dbSNP: rs63750973
rs63750973
APP
0.720 GeneticVariation UNIPROT

dbSNP: rs63751122
rs63751122
APP
0.710 GeneticVariation UNIPROT

dbSNP: rs63750264
rs63750264
APP
0.900 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63750671
rs63750671
APP
0.760 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63750734
rs63750734
APP
0.730 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63750064
rs63750064
APP
0.720 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63749964
rs63749964
APP
0.710 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63750399
rs63750399
APP
0.700 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs63750643
rs63750643
APP
0.700 GeneticVariation UNIPROT A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene. 15365148

2004
dbSNP: rs1468425505
rs1468425505
APP
0.020 GeneticVariation BEFREE A functional polymorphism in exon 2 of the cathepsin D gene (C-->T, Ala224Val) has recently been reported to increase the risk for AD in some of the Caucasian populations, with a significant overrepresentation of the T allele, but these reports have not been universally duplicated. 15211064

2004
dbSNP: rs63750264
rs63750264
APP
0.900 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750671
rs63750671
APP
0.760 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750066
rs63750066
APP
0.730 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750734
rs63750734
APP
0.730 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750064
rs63750064
APP
0.720 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63749964
rs63749964
APP
0.710 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750399
rs63750399
APP
0.700 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750643
rs63750643
APP
0.700 GeneticVariation UNIPROT A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease. 8577393

1995
dbSNP: rs63750264
rs63750264
APP
A 0.900 CausalMutation CLINVAR A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. 1925564

1991
dbSNP: rs63750264
rs63750264
APP
T 0.900 CausalMutation CLINVAR A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. 1925564

1991
dbSNP: rs63750264
rs63750264
APP
0.900 GeneticVariation UNIPROT A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43). 9328472

1997
dbSNP: rs63750671
rs63750671
APP
0.760 GeneticVariation UNIPROT A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43). 9328472

1997
dbSNP: rs63750066
rs63750066
APP
0.730 GeneticVariation UNIPROT A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43). 9328472

1997