|
rs3818361
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs3818361
|
|
|
0.880 |
GeneticVariation |
GWASCAT |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.
|
21460840 |
2011 |
|
rs3818361
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Meta-analysis of available studies (n = 31,771 individuals), including previous studies and public genome-wide association study resources (Alzheimer's Disease Neuroimaging Initiative, Translational Genomics Research Institute, and Multi-site Collaborative Study for Genotype-Phenotype Associations in Alzheimer's Disease), strongly supports the effect of rs3818361 (odds ratio = 1.180, 95% confidence interval: 1.113-1.252, P < 2.99E-8) and suggests the existence of between-study heterogeneity (P < .05).
|
21784344 |
2011 |
|
rs3818361
|
|
|
0.880 |
GeneticVariation |
BEFREE |
Unadjusted, CLU (odds ratio [OR], 0.91; 95% confidence interval [CI], 0.85-0.96 for single-nucleotide polymorphism [SNP] rs11136000), CR1 (OR, 1.14; 95% CI, 1.07-1.22; SNP rs3818361), and PICALM (OR, 0.89; 95% CI, 0.84-0.94, SNP rs3851179) were associated with AD in white individuals.
|
20697030 |
2010 |
|
rs3818361
|
|
|
0.880 |
GeneticVariation |
BEFREE |
The results revealed that there were significant differences in genotype (P=0.02) and allele (P=0.007) frequencies of the SNP rs6656401 but no in rs3818361 between AD patients and controls.
|
20558149 |
2010 |
|
rs3818361
|
|
A |
0.880 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
rs3818361
|
|
|
0.880 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease.
|
19734903 |
2009 |
|
rs6701713
|
|
|
0.810 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs6701713
|
|
|
0.810 |
GeneticVariation |
BEFREE |
In this case-control study, we aimed to investigate whether single nucleotide polymorphisms in MTHFR (rs1801133), PICALM (3851719), CLU (rs11136000), and CR1 (rs6701713) are associated with AD.
|
25359311 |
2015 |
|
rs6701713
|
|
A |
0.810 |
GeneticVariation |
GWASCAT |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs6701713
|
|
A |
0.810 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs4844610
|
|
|
0.710 |
GeneticVariation |
BEFREE |
Individuals with F/S genotype had a 1.8 times increased risk for AD compared with F/F genotype (p-adjusted = 0.003), while rs4844610 was only marginally significant (p-adjusted = 0.024).
|
22819390 |
2012 |
|
rs4844610
|
|
|
0.710 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs2093760
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
|
30617256 |
2019 |
|
rs12036785
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs679515
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
A novel Alzheimer disease locus located near the gene encoding tau protein.
|
25778476 |
2016 |
|
rs1408077
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs1408078
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs2296160
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs1344800847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In AD patients carrying the H allele (<i>Hin</i>dIII polymorphism) or the Q allele (Q981H polymorphism), CR1/E was significantly lower when compared with controls carrying the same alleles (<i>p</i> < 0.01), contrary to sCR1, which was significantly higher (<i>p</i> < 0.001).
|
30044434 |
2018 |
|
rs3738467
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In AD patients carrying the H allele (<i>Hin</i>dIII polymorphism) or the Q allele (Q981H polymorphism), CR1/E was significantly lower when compared with controls carrying the same alleles (<i>p</i> < 0.01), contrary to sCR1, which was significantly higher (<i>p</i> < 0.001).
|
30044434 |
2018 |
|
rs4844609
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Ser1610Thr variant was not associated with AD</span>, memory impairment, total tau, amyloid β(1-42) or tau phosphorylated at threonine 181 levels.
|
23582656 |
2013 |