|
rs17643262
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs17643262
|
|
A |
0.800 |
GeneticVariation |
GWASDB |
SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
|
23565137 |
2013 |
|
rs17643262
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs1800795
|
|
|
0.720 |
GeneticVariation |
BEFREE |
In this case-control study, we aimed to investigate whether single nucleotide polymorphisms in the BIN1 (rs744373) and IL-6 (rs1800795) genes are associated with AD.
|
26733302 |
2016 |
|
rs1800795
|
|
|
0.720 |
GeneticVariation |
GWASCAT |
A potential endophenotype for Alzheimer's disease: cerebrospinal fluid clusterin.
|
26545630 |
2016 |
|
rs1800795
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Regression analysis revealed that the presence of both rs1801133 T and rs1800795 C alleles increased the odds of developing AD by 2.5 and VaD by 3.7-fold.
|
22015309 |
2012 |
|
rs10408847
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs12461065
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs138137383
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs145903417
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs536518226
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs117161928
|
|
A |
0.700 |
GeneticVariation |
GWASCAT |
Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
|
26830138 |
2016 |
|
rs1048699
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs1114831
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs1114832
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
|
21460841 |
2011 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
The meta-analysis suggests that there is no enough evidence for associations of A2M gene polymorphisms (5 bp I/D, Ile1000Val) with AD risk at present, even after stratification by ethnicity and APOE ε4 with genotypes of polymorphism sites.
|
24756728 |
2014 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Through combination-analysis of the data about the A2M-I/D and the A2M-Ile1000Val variants, the A2M gene was suggested to be associated with Alzheimer's disease.
|
15931081 |
2005 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
Allelic frequencies with the I1000V polymorphism in the gene were 7.4 and 6.8% in the control and AD groups, respectively.
|
10936700 |
2000 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In contrast, there was no relationship between the alpha2m Val1000Ile polymorphism and Alzheimer's disease in these families.
|
10688047 |
2000 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
To evaluate the genetic factors for AD among a Chinese population in Taiwan, we studied the polymorphisms of six candidate genes of Alzheimer's disease (AD), including the regulatory region of apolipoprotein E (Apo-E, G-186T), the promoter of apolipoprotein E (Apo-E, A-491T), the bleomycin hydrolase gene (BH, A1450G), a mutation of alpha(2)-macroglobulin gene (A2M G2998A), low-density lipoprotein receptor-related protein gene (LRP, C766T), and alpha(1)-antichymotrypsin gene (ACT, -15Ala/Thr) in AD patients and non-affected elder individuals among Taiwanese Chinese.
|
11099722 |
2000 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
In the present study we tested two polymorphisms in the alpha-2 macroglobulin gene, a 5 bp deletion at the 5' splice site of exon 18 and a G/A point mutation (V1000I) in exon 24, in a sample of 118 healthy, non demented controls and 238 consecutively recruited gerontopsychiatric patients, diagnosed as: Alzheimer's disease (N=88), mild cognitive impairment (N=32), subjective cognitive complaints (N=54) and depression/other psychiatric disorders (N=64).
|
11058789 |
2000 |
|
rs669
|
|
|
0.070 |
GeneticVariation |
BEFREE |
No association between the alpha-2 macroglobulin I1000V polymorphism and Alzheimer's disease.
|
10203250 |
1999 |
|
rs3832852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Accumulating studies have evaluated the association of Alpha-2-Macroglobulin gene (A2M) 5 bp insertion/deletion (5 bp I/D, rs3832852) and Ile1000Val (rs669) polymorphisms with Alzheimer's disease (AD) risk, but the results remain inconclusive.
|
24756728 |
2014 |