rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In summary, the present meta-analysis suggests that the PPAR-γ rs1801282 polymorphism may not be associated with genetic susceptibility of AD in general population.
|
25770052 |
2015 |
rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This meta-analysis has shown that there is a lack of association between the PPARγ Pro12Ala and His447His polymorphisms and AD risk.
|
26125935 |
2015 |
rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This meta-analysis identified an association between AD and the COMT Val158Met polymorphism in Asians but not in Europeans, but it revealed no association between AD and the PPARγ Pro12Ala polymorphism.
|
24477323 |
2014 |
rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
These findings suggest that the functional PPAR-gamma Pro12Ala polymorphism may modify the age at onset of AD.
|
19631630 |
2009 |
rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The peroxisome proliferator-activated receptor gamma (PPAR-gamma2) Pro12Ala polymorphism is associated with higher risk for Alzheimer's disease in octogenarians.
|
17270153 |
2007 |
rs1801282
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We found that PPARgamma Pro12Ala polymorphism influenced plasma 24S-hydroxycholesterol/ cholesterol ratios in AD patients in that carriers of the Ala allele presented with higher ratios than homozygote carriers of the Pro-allele.
|
15666037 |
2005 |
rs1805192
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis has shown that there is a lack of association between the PPARγ Pro12Ala and His447His polymorphisms and AD risk.
|
26125935 |
2015 |
rs1805192
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This meta-analysis identified an association between AD and the COMT Val158Met polymorphism in Asians but not in Europeans, but it revealed no association between AD and the PPARγ Pro12Ala polymorphism.
|
24477323 |
2014 |
rs1805192
|
|
|
0.050 |
GeneticVariation |
BEFREE |
These findings suggest that the functional PPAR-gamma Pro12Ala polymorphism may modify the age at onset of AD.
|
19631630 |
2009 |
rs1805192
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The peroxisome proliferator-activated receptor gamma (PPAR-gamma2) Pro12Ala polymorphism is associated with higher risk for Alzheimer's disease in octogenarians.
|
17270153 |
2007 |
rs1805192
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We found that PPARgamma Pro12Ala polymorphism influenced plasma 24S-hydroxycholesterol/ cholesterol ratios in AD patients in that carriers of the Ala allele presented with higher ratios than homozygote carriers of the Pro-allele.
|
15666037 |
2005 |
rs1151999
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PPAR-γ TCCA haplotype derived from SNPs in introns 4 (rs4135263), 5 (rs1151999), and 6 (rs709149 and rs709154) showed a strong protective effect against AD in APOE ε4 allele noncarriers (p=0.001, permutation p=0.006, Bonferroni corrected p=0.021), with a frequency of 39% in cases and 50% in controls.
|
19660836 |
2011 |
rs4135263
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PPAR-γ TCCA haplotype derived from SNPs in introns 4 (rs4135263), 5 (rs1151999), and 6 (rs709149 and rs709154) showed a strong protective effect against AD in APOE ε4 allele noncarriers (p=0.001, permutation p=0.006, Bonferroni corrected p=0.021), with a frequency of 39% in cases and 50% in controls.
|
19660836 |
2011 |
rs709149
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PPAR-γ TCCA haplotype derived from SNPs in introns 4 (rs4135263), 5 (rs1151999), and 6 (rs709149 and rs709154) showed a strong protective effect against AD in APOE ε4 allele noncarriers (p=0.001, permutation p=0.006, Bonferroni corrected p=0.021), with a frequency of 39% in cases and 50% in controls.
|
19660836 |
2011 |
rs709154
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The PPAR-γ TCCA haplotype derived from SNPs in introns 4 (rs4135263), 5 (rs1151999), and 6 (rs709149 and rs709154) showed a strong protective effect against AD in APOE ε4 allele noncarriers (p=0.001, permutation p=0.006, Bonferroni corrected p=0.021), with a frequency of 39% in cases and 50% in controls.
|
19660836 |
2011 |