| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.700 | GeneticVariation | GWASCAT | Detection and interpretation of shared genetic influences on 42 human traits. | 27182965 | 2016 |
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|
0.060 | GeneticVariation | BEFREE | GAC haplotype from rs4730125, rs6967330, and rs408223 was associated with pre-school current wheeze and school-age asthma. | 31610042 | 2020 |
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|
0.060 | GeneticVariation | BEFREE | A <i>CDHR3</i> SNP (rs6967330) with G to A base change has been linked to severe exacerbations of asthma and increased susceptibility to RV-C infections in young children. | 30916989 | 2019 |
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|
0.060 | GeneticVariation | BEFREE | The CDHR3 asthma risk allele (rs6967330-A) was associated with increased risk of respiratory tract illnesses (incidence risk ratio [IRR] = 1.14 [95% confidence interval, 1.05-1.23]; P = 0.003). | 29121479 | 2018 |
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|
0.060 | GeneticVariation | BEFREE | A single nucleotide polymorphism (rs6967330, encoding C529Y) in CDHR3 regulates the display density of CDHR3 on cell surfaces and is among the strongest known genetic correlates for childhood virus-induced asthma susceptibility. | 30532249 | 2018 |
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|
0.060 | GeneticVariation | BEFREE | The odds ratios (ORs) for association of the A allele at rs6967330 with adult asthma were calculated according to age at onset of asthma. | 28318885 | 2017 |
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|
0.060 | GeneticVariation | BEFREE | Our findings identify that the asthma susceptibility gene product CDHR3 mediates RV-C entry into host cells, and suggest that rs6967330 mutation could be a risk factor for RV-C wheezing illnesses. | 25848009 | 2015 |
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|
0.010 | GeneticVariation | BEFREE | GAC haplotype from rs4730125, rs6967330, and rs408223 was associated with pre-school current wheeze and school-age asthma. | 31610042 | 2020 |