|
rs2275913
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, our data indicate that IL-17A rs2275913 polymorphism but not IL-17F rs763780 polymorphism contributes to increased risk for CRC patients in this Chinese population.
|
31682719 |
2019 |
|
rs2275913
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We observed significant association between rs2275913 in IL-17A and susceptibility to CRC</span> (<i>p</i> = 0.016228).
|
30233234 |
2018 |
|
rs2275913
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Some studies have previously shown that IL-17A and IL-17F polymorphisms, respectively rs2275913 and rs763780, are associated with gastric or colorectal cancer risk.
|
28347290 |
2017 |
|
rs2275913
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A case-control study of 401 cases and 300 sex- and age-matched controls was performed in order to explore the role of IL1B_1473G/C (rs1143623), SOD1_7958A/G (rs4998557), TLR4_1196C/T (rs4986791), IL10_1082A/G (rs1800896), IL17A_197G/A (rs2275913), and TLR4_896A/G (rs4986790) polymorphisms in the susceptibility to colorectal cancer (n = 244), gastric carcinoma (n = 72), and ovarian cancer (n = 85).
|
24446182 |
2014 |
|
rs2275913
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We have investigated the association between colorectal cancer and polymorphisms of IL17A (rs2275913.G197A).
|
24699997 |
2014 |
|
rs148704956
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The IL-17A G197A variant may be utilized as a genetic screening marker in assessing CRC risk, and its expression can be used as a biomarker for early detection of CRC in the Saudi population.
|
30233234 |
2018 |
|
rs148704956
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Association between polymorphisms of interleukin-17A G197A and interleukin-17F A7488G and risk of colorectal cancer.
|
29970680 |
2018 |
|
rs148704956
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We also observed a significant association between the AG genotype of IL-17A G197A SNP with increased risk of colorectal cancer as compared to AA genotype (P=0.001).
|
25680555 |
2015 |
|
rs148704956
|
|
|
0.040 |
GeneticVariation |
BEFREE |
We have noted a significant association of IL17A G197A polymorphism not only with tumor localization (p = 0.003) but also with tumor differentiation (p = 0.0005) in CRC patients.
|
24699997 |
2014 |
|
rs3748067
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MAF of rs3748067 was significantly higher in CRC cases resistant to FOLFOX treatment (R+) than non resistant (R-).
|
31138901 |
2019 |
|
rs3748067
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Heterozygous rs10484879 [OR (95% CI) = 2.63 (1.64-4.21)] was associated with higher risk, while carriage of heterozygous rs3748067 genotype was associated with reduced risk of CRC [OR (95% CI) = 0.56 (0.37-0.84)], respectively.
|
29689450 |
2018 |
|
rs10484879
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs10484879 SNP, and IL-17A haplotypes AGGTG and GAGTG constitute independent factors of CRC susceptibility.
|
29689450 |
2018 |